BACKGROUND There have been genetic studies assessing the association between tumor necrosis factor (TNF)-α-308 and Kawasaki disease (KD) but the results have been conflicting due to lack of power. Therefore, a systematic review and meta-analysis was conducted to increase the power for identifying the association between the TNF-α-308 polymorphism and KD. METHOD Studies were identified from ME...

Incidence and clinical features of kawasaki disease in Catalonia (Spain) Judith Sanchez-Manubens, Jordi Anton, Fredy Prada, Rosa Bou, Estibaliz Iglesias, Joan Calzada-Hernandez, Vicenç Torrente-Segarra, Samuel Hernandez, Silvia Ricart, Marc Tobeña, Anna Fernandez, Montserrat Gispert-Sauch, Aina Sanchez, Mariona Bonet, Neus Rius, Sonia Corral, Olga Calavia, Kawasaki Disease in Catalonia Working ...

This is the first in a series of two papers in which we derive a Γ-expansion for a two-dimensional non-local Ginzburg-Landau energy with Coulomb repulsion, also known as the Ohta-Kawasaki model in connection with diblock copolymer systems. In that model, two phases appear, which interact via a nonlocal Coulomb type energy. We focus on the regime where one of the phases has very small volume fra...

Kawasaki disease (KD) is an extremely rare condition in infants younger than 3 months old. Cardiovascular complications are unfortunately most common in young infants and it is in this age group, incomplete Kawasaki disease (IKD) is more frequently reported. Because IKD is a diagnostic dilemma, any sign that could help early diagnosis, such as BCG reactivation is useful. Here we report on an in...

PURPOSE Exaggerated pro-inflammatory reactions during the acute phase of Kawasaki disease (KD) suggest the role of immune dysregulation in the pathogenesis of KD. We investigated the profiles of T regulatory cells and their correlation with the clinical course of KD. METHODS Peripheral blood mononuclear cells were collected from 17 KD patients during acute febrile and subacute afebrile phases...

BACKGROUND AND OBJECTIVES About 10-15% of Kawasaki disease (KD) is refractory to intravenous immunoglobulin (IVIG) therapy. This study was designed to investigate the predicting factors for refractory KD. SUBJECTS AND METHODS We reviewed retrospectively the clinical records of 77 patients with typical KD admitted at Wonju Christian Hospital from January, 2005, to December, 2008. The variance ...

Elevated serum levels of interleukin-10 (IL-10) have been reported in patients with Kawasaki disease (KD). IL-10 reduces the inflammatory actions of macrophages and T cells and it may play a significant role in the regulation of inflammatory vascular damage associated with systemic vasculitis. The aim of this study was to examine whether -592 IL-10 promoter polymorphism is a susceptibility or s...

Coronary artery complications from Kawasaki disease (KD) range from no involvement to giant coronary artery aneurysms (CAA). Current long-term management protocols are calibrated to the degree of maximal and current coronary artery involvement reflecting the known likelihood of severe long-term cardiac complications. It has recently been suggested that all KD patients may be at potential risk o...

background: contralateral axillary metastasis (cam) is a rare entity in patients with breast cancer which can occur during the primary breast cancer or its follow-up. different treatment modalities include surgery, radiotherapy, and chemotherapy, but there is no agreement on them. in our review, we found 12 series with available data, 82 patients with synchronous or metachronous contralateral a...

introduction: breast cancer is the most common cancer and the second cause of death in women. it is essential to have the highest level of confidence in axillary staging assessment. many surgeons and pathologists believe that fewer lymph nodes are present in axillary dissection specimens of women treated by neoadjuvant chemotherapy. consequently, the purpose of this study was to compare the lym...