By using biotin labelled proteoglycan core protein and an avidin enzyme system, hyaluronan (hyaluronic acid) was visualised in specimens of human jejunum. Intense staining for hyaluronan was seen in the loose connective tissue of the villi and of lamina propria while the epithelial layer was unstained. The muscularis mucosae showed only faint staining. The accumulation of hyaluronan in the sube...

Case Description- A six-month-old Doberman Pinscher male with sever laceration in the mucosa of the lip, nose and nostrils as well as the shoulder area was referred to Veterinary Hospital of Shahid Bahonar University of Kerman. Clinical Findings- The animal showed anorexia, depression, and sialorrhea. There was also a deep laceration over the right should...

Cao, Weibiao, Claudio Fiocchi, and Victor E. Pricolo. Production of IL-1 , hydrogen peroxide, and nitric oxide by colonic mucosa decreases sigmoid smooth muscle contractility in ulcerative colitis. Am J Physiol Cell Physiol 289: C1408–C1416, 2005. First published July 20, 2005; doi:10.1152/ajpcell.00073.2005.—We have previously shown that sigmoid circular muscle cells from patients with ulcerat...

Platelet-activating factor (PAF) and interleukin-6 (IL-6) are produced in the esophagus in response to HCl and affect ACh release, causing changes in esophageal motor function similar to esophagitis (Cheng L, Cao W, Fiocchi C, Behar J, Biancani P, and Harnett KM. Am J Physiol Gastrointest Liver Physiol 289: G418-G428, 2005). We therefore examined HCl-activated mechanisms for production of PAF a...

The aim of the research was to study nature structural and functional features epithelium oral mucosa tongue laboratory animals as a result exposure broadband red light. As morphological electron microscopic analysis changes rats after light revealed absence severe, irreversible in epithelium, submucous layer its components, weak severity reversibility circulatory disorders tissues. data obtain...

Buccal delivery of saquinavir has the advantage to bypass hepatic first-pass metabolism associated with oral administration. Local microenvironmental pH (pHM) modification at buccal mucosa might increase absorption by balancing solubility and partition into mucosa. The present study aimed evaluate a novel pHM modifying film using effervescence, as well elucidate relationship between permeation ...

background and aim: oral mucosal lesions have various prevalence rates among different populations. few studies have evaluated the frequency of oral mucosal lesions in iranian population. this study aimed to determine the frequency of oral mucosal lesions and the related factors.                        materials and methods: this descriptive study was conducted based on the data in the archives...

tuberculosis is a major cause of morbidity and mortality worldwide. it is a chronic granulomatous disease that can affect any part of the body, including the oral cavity. oral lesions of tuberculosis, though uncommon, are seen in both the primary and secondary stages of the disease. this article presents a case of tuberculosis of the buccal mucosa, manifesting as non-healing, non-painful ulcer....

metastatic tumors to the heart unlike primary cardiac tumors are not rare. despite its frequency, cardiac metastasis is commonly detected only during autopsy as the symptoms of disseminated metastasis prevail over symptoms caused by cardiac metastasis and hence is overlooked most of the time. tumors more commonly found metastasizing to the heart are malignancies of lung, breast, esophagus, lymp...