BACKGROUND Treatment of head and neck cancer is complex, and a multidisciplinary clinic may improve the coordination of care. The value of a head and neck multidisciplinary clinic has not yet been established in oropharyngeal squamous cell carcinoma (SCC). METHODS A retrospective review was conducted of Veterans Affairs patients with oropharyngeal SCC undergoing concurrent chemoradiation befo...

‘First and foremost we must, as a profession, become more ‘‘carcinoma-minded’’ in regard to the lungs’. No-one would disagree, but this statement was made by RC Brock, later Lord Brock, nearly 60 years ago in the British Medical Journal. Carcinoma of the bronchus still remains the most common cancer in men and the second most common cancer in women. In England there are approximately 32 000 dea...

Introduction This chapter reviews the theoretical and empirical literature on the concept of credibility and its areas of application relevant to information science and technology, encompassing several disciplinary approaches. An information seeker's environment—the Internet, television, newspapers, schools, libraries, bookstores, and social networks—abounds with information resources that nee...

Patients with hepatic metastases from colorectal cancer have a poor prognosis, with a median survival of less than 12 months. Although chemotherapy may have a beneficial effect on the natural history of unresected liver metastases, 5-year survival is difficult to achieve by chemotherapy alone. Hepatic resection can achieve prolonged survival with an acceptable mortality risk in selected patient...

A biosimilar is an officially regulated and approved copy of an originator biologic therapy. Improved affordability and consequent wider patient access compared with biologics are a significant appeal of biosimilars. Regulatory guidelines for biosimilar development and approval are rigorous and undergoing constant refinement. The process of licensing approval for all biosimilars requires demons...

This chapter looks at leadership and management of multidisciplinary teams in the mental health context. It provides an overview of what constitutes a multidisciplinary team and how policy can change the roles and relationships in teams. The potential conflict inherent in teamwork is outlined. A brief overview of leadership styles is provided, with a more detailed description of the relationshi...

Since the early 1990s, significant advances have been made in cancer management. Increased specialization within disciplines and more-sophisticated treatment techniques have increased the complexity of patient care. As a result, patient management has become very multidisciplinary in nature, leading to the concept of multidisciplinary cancer conferences (mccs). The mccs bring together various m...

Many imaging modalities and scanning techniques, such as contrast enhanced CT, MRI and FDG-PET, are available for assessment of recurrent colorectal carcinoma. In addition, integrated PET/CT is becoming increasingly available. Intuitively, a synergistic combination of scanning characteristics sounds promising. However, the exact clinical value has not yet been fully established. The role of PET...

Neuroendocrine tumours (NETs) are very rare diseases characterised by a high degree of histological and clinical heterogeneity. They can be silent (even producing some hormones) or clinically evident as a result of local growth and/or hormonal production. The diagnostic and therapeutic approach to patients with NETs should be multidisciplinary. A medical oncologist should coordinate a group of ...

This paper is a theoretical and empirically informed examination of the naturalist distinction between withholding and withdrawing life-support. Drawing on the history of mechanical ventilation and on a recent Israeli law containing a novel approach to disconnecting life-support at the end of life, it is argued that the design of machines predicate the division line between “active” and “passiv...