Background: Since in multiple sclerosis (MS), changes in speech and voice quality often precede other signs and symptoms; early diagnosis of these changes is necessary. In this study, an acoustic examination of phonation subsystem was performed. Due to the progressive nature of multiple sclerosis, the aim of this study was to examine the correlation between acoustic parameters ...

multiple sclerosis (ms) is a chronic inflammatory disease that leads to degeneration of the brain and spinal tissue. imbalances of cd4+ t cells including thelper1 (th1)/thelper2 (th2) and thelper17 (th17)/tregulatory (treg), their secreted cytokines and gene expressions, are important aspects of in immunopathogenesis of ms. vitamin a and its metabolites can regulate the immune system and appear...

OBJECTIVE The current study examined driver behaviors and patterns among drivers with multiple sclerosis (MS) as a function of disease severity and in comparison to drivers without MS. DESIGN Between-group comparisons of participants with and without MS and cohorts of MS groups at varying levels of severity. SETTING All data were collected in an outpatient research setting. PARTICIPANTS C...

in this study, the artificial neural networks (anns) and regression models were used to downscale the simulated outputs of the general circulation models (gcms). the simulated precipitation for 25.18 º n to 34.51 º n and 45 º e to 60 º e, geopotential height at 850 mb and zonal wind at 200 mb for 12.56° n to 43.25° n and 19.68° e to 61.87° e data sets as the predictors were extracted from echam...

BACKGROUND Social participation is an integral part of everyday life in society; however, evidence about its association with health-related quality of life (HRQoL) in people with multiple sclerosis (MS) is lacking. OBJECTIVE The aim of this study is to explore whether social participation is associated with the Physical Component Summary of HRQoL (PCS) and Mental Component Summary of HRQoL (...

BACKGROUND Patient outcomes in multiple sclerosis (MS) have generally been measured by their neurological impairment using specific scales such as the Kurtzke Expanded Disability Status Scale (EDSS). However, this scale does not measure the multiple dimensions of health-related quality of life (HRQOL) such as functional status and general well-being, which are also important outcomes along with...