It has been well established that oxidative stress contributes to pathology associated with Duchenne muscular dystrophy (DMD). I hypothesized that overexpression of the antioxidant enzyme catalase would improve muscle function in the mdx mouse, the mouse model of DMD. To test this hypothesis, neonatal mdx mice were injected with a recombinant adeno-associated virus driving the catalase transgen...

BACKGROUND Facial lines and wrinkles are strongly influenced by individual differences in anatomy and muscle activity and no single injection protocol will suit all patients. However, there is only limited information in the published literature on how to develop a tailored approach to botulinum toxin treatment. METHODS An expert panel of physicians was convened to establish a consensus on de...

Outbreak of Mycobacterium tuberculosis infections associated with acupuncture has not been reported. Thirteen patients with a painful swollen lump were referred to our hospital. The index patient received acupuncture and paraspinal muscular injection at a local acupuncture clinic in April 2011 and was diagnosed with M. tuberculosis 1 month later. From May 2011 to August 2011, 12 more patients w...

how to cite this article: rashnonejad a, onay h, atik t, atan sahin o, gokben s, tekgul h, ozkinay f. molecular genetic analysis of survival motor neuron gene in 460 turkish cases with suspicious spinal muscular atrophy disease. iran j child neurol. autumn 2016; 10(4):30-35. abstract objective to describe 12 yr experience of molecular genetic diagnosis of spinal muscular atrophy (sma) in 460 ca...

OBJECTIVE To investigate whether the volume of solution used to inject equivalent units of botulinum exotoxin A affects the diffusion of toxin and areas of rhytid diminution in the treatment of dynamic forehead lines. DESIGN Ten volunteers with dynamic forehead lines were included. Each study patient received a single injection at a point 2.5 cm above the orbital rim on either side of the for...

267 We read with interest the article by Kim and colleagues [1] entitled “Nicolau’s syndrome after intramuscular injection: 3 cases.” Recently, we published a case report in The Journal of Dermatology about embolia cutis medicamentosa [2]. Herewith, we highlight the lethal potential and the possible serious complications of this syndrome by reporting a case of complicated life-threatening Nicol...

purpose: to evaluate the effects of intravitreal and intracameral injection of bevacizumab in patients with neovascular glaucoma (nvg).   methods: this interventional case series was conducted on 40 eyes of 40 patients with neovascular glaucoma. data included the extent of iris (nvi) and angle neovascularization (nva), peripheral anterior synechia (pas), and intraocular pressure (iop). followin...