,....-,HE SYNERGISTIC combination of immunosuppres.1 sive drugs is thought to provide a better therapeutic index with fewer side effects than single-drug therapy. Tacrolimus (FK 506), an inhibitor of interleukin-2 (IL-2) synthesis, is a potent immunosuppressive agent that has various adverse effects including nephrotoxicity, neurotoxicity, diabetogenesis. and infectious complications.! Experime...

Rituximab and mycophenolate mofetil are used to treat pemphigus vulgaris, but they have not been adequately compared in clinical trials.

BACKGROUND New-onset diabetes after transplant (NODAT) is a serious complication after kidney transplantation. We studied the relationship between steroid-free maintenance regimens and NODAT in a national cohort of adult kidney transplant patients. METHODS A total of 25,837 previously nondiabetic kidney transplant patients, engrafted between January 1, 2004, and December 31, 2006, were includ...