OBJECTIVE In adults with an interarterial and intramural course of an anomalous right coronary artery from the left sinus (AAORCA), surgical unroofing is recommended in the setting of myocardial ischaemia. However, data regarding functional testing are limited, and the management of adults without ischaemia is unclear. To evaluate these patients, we employed an exercise N(13)-ammonia positron e...

OBJECTIVE To determine the acute effects of pyridostigmine bromide, a reversible cholinesterase inhibitor, during exercise in patients with coronary artery disease. DESIGN Double blind, randomised, placebo controlled, crossover study. SETTING Outpatients evaluated in an exercise test laboratory. PATIENTS 15 patients with exercise induced myocardial ischaemia. INTERVENTIONS Maximal cardi...

The angiopoietins and Tie receptors are involved in blood vessel formation. The role of the angiopoietin/Tie receptor system in myocardial ischaemia/reperfusion is not well known. To investigate the participation of angiopoietins and Tie receptors in myocardial ischaemia/reperfusion, adult Wistar rats were studied in which the left coronary artery was ligated for 30 min, followed by reperfusion...

Sir,—We did not study the Belscope with the prism attached. The instructions with the Belscope state that the prism is only needed three times per 1000 intubations and is not recommended for routine use, as the medium restricts the field of view. The instructions state, and this is borne out by our experience, that where the difficulty of laryngoscopy requires the prism to be used, the tracheal...

[7] Wiggers CJ. Are ventricular conduction changes of importance in the dynamics of ventricular contraction? Am J Physiol 1927; 12-30. [8] Xiao HB, Roy C, Gibson DG. Nature of ventricular activation in patients with dilated cardiomyopathy: evidence for bilateral bundle branch block. Br Heart J 1994; 72: 167-74. [9] Ng KSK, Gibson DG. Impairment of diastolic function by shortened filling period ...

Studies were made using ordinary selective coronary angiography and angiography during ischaemia produced by right atrial pacing, on a series of 41 patients with ischaemic heart disease, to examine the response of the collaterals to the ischaemia stimulus. Regional myocardial perfusion was determined under the same circumstances by measuring regional 133Xenon washout curves. No collaterals were...