Background: Pre-clinical investigation of stem cells for repairing damaged myocardium predominantly used rodents, however large animals have cardiac circulation closely resembling the human heart. The aim of this study was to evaluate whether SPECT/CT myocardial perfusion imaging (MPI) could be used for assessing sheep myocardium following an acute myocardial infarction (MI) and response to int...

Fixed myocardial defects in both stress and rest images, could be artifactual as a result of soft tissue attenuation. To increase specificity and identify the false positive results, we used gated technique to evaluate the wall motion and wall thickening as an index to differentiate real ischemic lesions from artifactual defects. 93 patients were studied. In 46 patients (48.8%) fixed perf...

With the introduction of the concurrent myocardial blood flow (MBF) quantification in ml/g/min with positron emission tomography/computed tomography (PET/CT) assessment of myocardial perfusion in clinical routine, the scope of conventional scintigraphic myocardial perfusion imaging now expands from the identification of the most advanced and culprit CAD lesion, as signified by the stress-induce...

It is fair to state that interpretation of SPECT myocardial perfusion images, as with most scintigraphic studies, reflects a mixture of art and science. Increasingly, efforts have been, and are being, made to improve the diagnostic accuracy of SPECT myocardial perfusion imaging (MPI) by enhancing image quality while at the same time reducing radiation burden, via the scientific, technologic app...

We present static and dynamic techniques to visualize perfusion data and to relate perfusion data to morphologic image data. In particular, we describe the integrated analysis of MRI myocardial perfusion data with CT coronary angiographies depicting the morphology. We refined the Bull’s-Eye Plot, a wide-spread and accepted analysis tool in cardiac diagnosis, to show aggregated information of pe...

Large area detector computed tomography systems with fast rotating gantries enable volumetric dynamic cardiac perfusion studies. Prospectively, ECG-triggered acquisitions limit the data acquisition to a predefined cardiac phase and thereby reduce x-ray dose and limit motion artefacts. Even in the case of highly accurate prospective triggering and stable heart rate, spatial misalignment of the c...

Myocardial contrast echocardiography (MCE) and two-dimensional speckle tracking (2D-STE) were used to detect left ventricular myocardial microcirculation perfusion systolic function in dilated cardiomyopathy (DCM) explore the relationship between two.

tion of hemodynamically significant coronary artery stenosis: incremental diagnostic value of dynamic CT-based myocardial perfusion imaging. of dynamic computed tomography adenosine stress myocardial perfusion imaging in estimating myocardial blood flow at various degrees of coronary artery stenosis using a porcine animal model. A et al. Computed tomography stress myocardial perfusion imaging i...

Although thallium-201 exercise scintigraphy has been established for the detection of myocardial ischemia and viability, little is known regarding the myocardial thallium-201 kinetics during angioplasty. Herein, we report a 77-year old man with angina pectoris, in whom serial myocardial imaging after a single dose of thallium-201 was helpful in identifying not only the culprit lesion and myocar...