etazolamide. After resolution of the corneal edema, the patient’s vision improved to 20/20. During the next year our patient experienced recurrent episodes of elevated intraocular pressure and was diagnosed as having Posner-Schlossman syndrome. There was no further visual field loss associated with her subsequent attacks of elevated pressures and no evidence of recurrence of NAION. Her visual f...

PURPOSE To identify the spectrum of clinical and fluorescein angiographic features of optic disc ischemia in patients younger than 50 years. METHODS This retrospective comparative case series from a university consultative neuro-ophthalmology practice consisted of two phases. The first compared 108 cases of nonarteritic anterior ischemic optic neuropathy in patients younger than 50 years (NAI...

BACKGROUND To evaluate the effect of a single intravitreal ranibizumab injection in eyes with acute nonarteritic ischemic optic neuropathy (NAION). SUBJECTS AND METHODS In this retrospective clinical data analysis, 17 eyes of sixteen patients who experienced a visual loss with duration of 15 days or less comprised the study group. In addition to standard ophthalmic examination, retinal nerve ...

AIM To review special safety topics associated with sildenafil and to document the tolerability of 50- and 100-mg doses, overall and by age, in men with erectile dysfunction (ED). METHODS Data were collated from 67 double-blind placebo-controlled (DBPC) trials (> 14,000 men) conducted by the manufacturer and from the manufacturer's postmarketing safety database (39,277 patients). The DBPC dat...

PURPOSE Nonarteritic anterior ischemic optic neuropathy (NAION) is an optic nerve infarct involving axons of retinal ganglion cell (RGC) neurons. The rodent NAION model (rAION) can use transgenic mouse strains to reveal unique characteristics about the effects of sudden optic nerve ischemia on RGCs and their axons. The impact of rAION on RGC stress patterns, RGC loss, and their axons after axon...