All enveloped viruses must bud through a cellular membrane in order to acquire their lipid bilayer, but little is known about this important stage in virus biogenesis. We have developed a quantitative biochemical assay to monitor the budding of Semliki Forest virus (SFV), an enveloped alphavirus that buds from the plasma membrane in a reaction requiring both viral spike proteins and nucleocapsi...

HIV-1, the agent of the AIDS pandemic, is an RNA virus that reverse transcribes its RNA genome (gRNA) into DNA, shortly after its entry into cells. Within cells, retroviral assembly requires thousands of structural Gag proteins and two copies of gRNA as well as cellular factors, which converge to the plasma membrane in a finely regulated timeline. In this process, the nucleocapsid domain of Gag...

let c be a field of subsets of a set i. also, let     1 i i be a non-decreasing positivesequence of real numbers such that 1, 1 0 1   i  and    11 i i . in this paper we prove thatbv of all the games of -bounded variation on c is a non-separable and norm dual banach space of thespace of simple games on c . we use this fact to establish the existence of a linear mapping t from...

Following random matrix theory, we study nearest neighbor spacing distribution (NNSD) of the eigenvalues of the adjacency matrix of various model networks, namely scale-free, small-world and random networks. Our analysis shows that, though spectral densities of these model networks are different, their eigenvalue fluctuations are same and follow Gaussian orthogonal ensemble (GOE) statistics. Se...

For the student in the early years of medicine, no general topic points out his inadequate knowledge more than does pulmonary physiology and function. At best, any acquaintance with the topic is in knowing a few isolated but ill-understood terms, and this poor background works in a vicious circle to ensure that this state will continue. Part of the reason for his lack of knowledge, no doubt, li...

Epidemiology is a field torn between practices of surveillance and methods analysis. Since the onset COVID-19, epidemiological expertise has been mostly identified with first, as dashboards case mortality rates took centre stage. However, since its establishment an academic in early 20th century, epidemiology’s have always impacted on how diseases are classified, knowledge collected, what kind ...

Background & Aim: German chamomile is one of the most important medicinal plants. So, assessment of genetic diversity and relationship among the traits are very essential in chamomile breeding programs. Determination of the best indirect selection criteria for genetic improvement of essence percent and dry flower yield of German chamomile (Matricaria chamomilla L.) populations...

I will move to the Department of Biochemistry at Oxford University on 1 April 2007 in order to occupy the newly established Chair of Integrative Systems Biology. At the moment I work at the Budapest University of Technology and Economics where I am leading the Research Group of Molecular Network Dynamics financed by Hungarian Academy of Sciences. I have started my scientific carrier as an exper...