نتایج جستجو برای: nasopharyngeal neoplasms
تعداد نتایج: 508326 فیلتر نتایج به سال:
Nasopharyngeal carcinoma is a common malignancy in Southern China. After radiotherapy and chemotherapy, a considerable proportion of patients with nasopharyngeal carcinoma suffered tumor relapse and metastasis. Cancer stemcells (CSC) have been shownwith resistanceagainst therapies and thus consideredas the initiator of recurrenceandmetastasis in tumors,where the antiapoptotic propertyofCSCsplay...
Syndromic craniosynostosis is associated with a high rate of respiratory difficulty, due mainly to midfacial hypoplasia. Nasopharyngeal airway establishment has been reported as the first-line approach to airway obstruction and may obviate the need for a highly invasive tracheotomy. No previous studies have compared airway obstruction status in syndromic craniosynostosis between cases requiring...
Background & Objective: A simple approach to prevent close contact in healthcare settings during the COVID-19 outbreak is to train patients to collect their own nasopharyngeal and oropharyngeal swabs and deliver them to medical laboratories to have them processed. The aim of our study was to c...
Epstein-Barr virus (EBV) infection is closely associated with undifferentiated nasopharyngeal carcinoma (NPC), strongly implicating a role for EBV in NPC pathogenesis; conversely, EBV infection is rarely detected in normal nasopharyngeal epithelial tissues. In general, EBV does not show a strong tropism for infecting human epithelial cells, and EBV infection in oropharyngeal epithelial cells is...
Postradiation nasopharyngeal necrosis is an important late effect of radiotherapy that affects prognosis in patients with nasopharyngeal carcinoma. In the present study, we reviewed the clinical and imaging features of 67 patients with pathologically diagnosed postradiation nasopharyngeal necrosis who were treated at Sun Yat-sen University Cancer Center between June 2006 and January 2010. Their...
Let-7a is frequently downregulated in various types of human cancer including nasopharyngeal carcinoma. However, the underlying mechanism of let-7a action in nasopharyngeal carcinoma remains elusive. In this study, we show that the enhancer of zeste homolog 2 (EZH2) is a direct target of let-7a in human nasopharyngeal carcinoma cells. The inhibiti...
Increasing the rate of neoplasms in industrial societies and its wide variety among ornamental and wild fishes in both fresh and salt waters are important. The effect of carcinogenic factors and the role of virus in tumor formation should be considered. In this study 10 3-month-olds Koi and Marble strains of fresh water Angelfish (Pterophyllum scalare), , with cauliflower lesions masses w...
Stroke causes significant mortality and morbidity. The clinical value of the nasopharyngeal snorkel was investigated in stroke patients with disorders of consciousness. A total of 155 stroke patients were randomly divided into two groups: a nasopharyngeal snorkel was used in the treatment group (n=78) and an oropharyngeal snorkel was used in the control group (n=77). The PaO2 and PCO2 of both g...
Nasopharyngeal carcinoma is highly prevalent in Southern China and Southeast Asia. To unveil the molecular basis of this endemic disease, high-resolution comparative genomic hybridization arrays were used for systematic investigation of genomic abnormalities in 26 nasopharyngeal carcinoma samples. A comprehensive picture of genetic lesions associated with tumorigenesis of nasopharyngeal carcino...
TFAP2A regulates nasopharyngeal carcinoma growth and survival by targeting HIF-1α signaling pathway.
TFAP2A is a transcription factor that orchestrates a variety of cell processes, including cell growth and tissue differentiation. However, the regulation of TFAP2A in human nasopharyngeal carcinoma tumorigenesis and its precise mechanism of action remain largely unknown. In this study, we investigated the biologic role and clinical significance of TFAP2A in nasopharyngeal carcinoma growth and p...
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