In the present study, gelatin microspheres containing ofloxacin were prepared by coacervation phase separation method and characterized by optical microscopy and scanning electron microscopy. The microspheres were analyzed for drug entrapment, bulk density, angle of repose, particle size and In-vitro release pattern. The effect of process variables on microsphere size was studied and based on t...

Department of Pharmaceutical Chemistry, Devsthali Vidyapeeth College of Pharmacy, Rudharpur, Uttrakhand – 263153, India Abstract Nimesulide is a second generation non–steroidal anti–inflammatory agent, which is widely used in the long term therapy of rheumatoid arthritis, in alleviating pain and inflammation. But its short half-life (only 3–4 hr), so its causes more fluctuation. After oral admi...

Collagen is a naturally occurring matrix polymer which is highly conserved across species. It is the predominant extra-cellular matrix component of most connective tissues within the mammalian body, comprising one third of all protein found within tissues. Collagens are extracellular and have a mainly structural role. Critical parameters including density, packing and orientation (or direction)...

This paper reviews current research, techniques for characterization and trends on the field of nanocomposites. Nanocomposites are new materials made with fillers which have nanosize. These materials have a big potential for applications in the automotive and aerospace industry as well as in construction, electrical applications and food packing. There is a tremendous interest for using bionano...

in the past decade, electrospinning as a facile and effective means in producing nanofibers with diameters ranging from microns down to a few nanometers has been developed and considered important. in this work, electrospinning of an interesting natural biopolymer, sodium alginate, has been investigated. the results showed that water solution of sodium alginate cannot be electrospun into nanofi...

BACKGROUND Natural polymers have been used as pharmaceutical excipients. They are easily available, cheap, less toxic andbiodegradable. Many of them have been identified and research is ongoing regarding their characterization. OBJECTIVE The present study depicts the extraction and characterization of Aegle marmelos derived polymer which can be used as a pharmaceutical excipient. MATERIAL A...

At present the pharmaceutical academia and industries are focusing on the use of natural materials and resources for development of pharmaceutical product. Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms to fulfill specific functions. Various natural polymers are widely being studied as a potential carrier material for site specific drug del...

Natural rubber composites filled with short natural fibers (flax and sawdust) were prepared by blending procedure and the elastomer cross-linking was carried out using benzoyl peroxide. The microbial degradation of composites was carried out by incubating with Aspergillus niger recognized for the ability to grow and degrade a broad range of substrates. The extent of biodegradation was evaluated...