The present study examined infant negativity and maternal symptomatology by term status in a predominately low-income, rural sample of 132 infants (66 late-preterm) and their mothers. Late-preterm and term infants were group-matched by race, income, and maternal age. Maternal depression and anxiety symptoms were measured with the Brief Symptom Inventory 18 (BSI-18) when infants were 2 and 6 mon...

An auditory oddball paradigm in humans generates a long-duration cortical negative potential, often referred to as mismatch negativity. Similar negativity has been documented in monkeys and cats, but it is controversial whether mismatch negativity also exists in awake rodents. To this end, we recorded cortical and hippocampal evoked responses in rats during alert immobility under a typical pass...

W hat would you estimate is the ratio of positive to negative statements in your office? Negative statements include unconstructive criticism, complaining, gossiping, blaming, and abusive language. Work environments with high levels of negative talk are often described as toxic. In a caring profession such as primary care, we hope that toxic environments are few and far between; however, even...

Resting 12-lead electrocardiographic records from 849 patients who underwent coronary cineangiographic studies were reviewed for U wave negativity without knowledge of the clinical data or angiographic results. In order to evaluate U wave negativity as an independent electrocardiographic sign, patients with significant Q waves in the anterior leads were excluded from the final data analysis lea...

Social evaluation is a mental process that leverages the preference toward prosocial partners (positivity bias) against the avoidance of antisocial individuals (negativity bias) in a cooperative context. The phenomenon is well-known in humans, and recently comparative investigations looked at the possible evolutionary origins. So far social evaluation has been investigated mainly in non-human a...

OBJECTIVE This study examines how the social environment is related to allostatic load (AL), a multisystem index of biological risk. METHOD A national sample of adults (N = 949) aged 34-84 rated their relationships with spouse, family, and friends at 2 time points 10 years apart. At the second time point, participants completed a biological protocol in which indices of autonomic, hypothalamic...

Monitoring of serum free immunoglobulin light chains (FLC) in 26 myeloma patients who achieved immunofixation negativity after allografting showed a decrease of FLC at a median of 128 days before immunofixation negativity. In patients who subsequently relapsed, a 25% increase of FLC was observed at a median of 98 days before immunofixation positivity.

Partner-specific perfectionistic concerns (PC) include concern over mistakes, self-criticism, and socially prescribed perfectionism as it pertains to one's partner. The social disconnection model proposes that PC influences well-being indirectly through interpersonal problems. Thus, we hypothesized that social negativity (expressed anger, hostility, and rejection) would mediate the relationship...

The aim of the paper is to describe a standardized "Integrative Neuroscience" Platform that can be applied to elucidate brain-body mechanisms. This infrastructure includes a theoretical integration (the INTEGRATE Model). To demonstrate this infrastructure, hypotheses from the INTEGRATE Model are applied in an example investigation of the cognitive, brain and body markers of individual differenc...