Neonatal diabetes mellitus is underdiagnosed in the neonatal period because of the metabolic adaptation capacities of the newborns. However, it is associated with increased risk of short- and long-term morbidity; when transient it may recurs in adulthood. It is important to improve screening and early management with appropriate guidelines.

BACKGROUND Gestational diabetes related morbidity increases along the continuum of the glycemic spectrum. Perinatal mortality, as a complication of gestational diabetes, has been little investigated. In early studies, an association was found, but in more recent ones it has not been confirmed. The Brazilian Study of Gestational Diabetes, a cohort of untreated pregnant women enrolled in the earl...

BACKGROUND Gestational diabetes is impaired carbohydrate metabolism first diagnosed in pregnancy. Knowledge of diabetes dates back to centuries before Christ. Objective was to describe maternal complications during antenatal period and Maternal and neonatal outcome in gestational diabetes mellitus. METHODS This Descriptive observational study was conducted at Department of Obstetrics and Gyna...

: Biallelic variants in the pancreas-specific transcription factor 1A (PTF1A) gene are a rare cause of permanent neonatal diabetes. We report case diabetes with unique clinical manifestations. The diagnosis affected infant was confirmed by insufficient endocrine and exocrine pancreas activity; however, normal imaging. Molecular analyses identified novel homozygous single nucleotide variant (Chr...

PURPOSE to determine the prevalence of adverse gestational and neonatal outcomes in women with a positive screening and negative diagnosis for gestational diabetes mellitus (GDM). METHODS a retrospective descriptive cross-sectional study was conducted from 2000 to 2009 on 409 women with positive screening for GDM. The maternal variables studied were: age, body mass index, history of cesarean ...

The most common monogenic cause of neonatal diabetes is mutation in KCNJ11, which encodes a potassium channel in pancreatic beta cells. Some mutations in this gene, including Q52R, have been described in association with neurological deficits, but never with hepatic involvement. We report the second case of neonatal diabetes in a patient with a KCNJ11/Q52R mutation. This patient's clinical cour...

  Introduction :Jaundice is the most common cause of hospitalization of infants in the first month of life. Delivery and maternal and neonatal risk factors may affect the progression of complications of jaundice. This study aimed to investigate the problems of pregnancy and delivery in neonates with jaundice. Methods: This descriptive study was performed on 2796 full term 3 to 29 day infants w...

OBJECTIVES There is a high prevalence of type 2 diabetes among Micronesians leading to the assumption that they are at an increased risk for gestational diabetes. The objective of this study was to determine the prevalence of gestational diabetes among the Micronesian population in Honolulu, Hawai'i. Secondary objectives were to determine factors associated with gestational diabetes and compare...

INTRODUCTION Regarding to the recent advances in assisted reproductive techniques (ART), twin and multiple pregnancies have increased during past years. OBJECTIVE This study was performed to compare obstetrics and perinatal outcomes of dichorionic twin pregnancy following ART with spontaneous pregnancy. MATERIALS AND METHODS In this cross-sectional study which was performed in Ghaem Hospita...