Nephrogenic systemic fibrosis (NSF) is a rare fibrosing disorder described among patients with renal disease. Currently, no standard therapy exists, although therapeutic modalities have included plasmapheresis, extracorporeal photopheresis, sodium thiosulphate, imatinib and renal transplantation. We describe a patient with NSF who was physically debilitated and underwent renal transplantation. ...

Magnetic resonance imaging (MRI) is now a commonly used imaging modality in many neurosurgical and neurological conditions. Although generally regarded as safe, there are a number of important safety considerations. These include a recently recognised, rare condition termed nephrogenic systemic fibrosis (NSF) that occurs in patients with significant renal impairment who receive gadolinium based...

Prior to the workshop, the attendees were asked to submit a one-page research statement describing current work (including citations and web pointers) and outlining future topics of research in scientific workflows. This document is a compilation of those statements, grouped according to the four planned discussion topics for the workshop. 1) Applications and requirements: What are the requirem...

We are sending you a draft version of the current list of recommendations of the ADVANCE Policy and Practices Review Initiative Committee (PPRI). This is a true draft. We will submit the draft to the campus community for comment and as an initial ideas sweep to see if there are additional recommendations that should be included in this document. The final version of this document will be includ...

Nephrogenic systemic fibrosis (NSF), first described in 2000 in a 15-patient case series, is an extremely debilitating, multisystemic fibrosing disorder. Since that initial report, more than 300 cases have been recognized, and their histopathologic features have been categorized. Two known associations with NSF are renal dysfunction and exposure to gadolinium (Gd)– containing magnetic resonance...

BACKGROUND In the past decade, more than 200 cases of nephrogenic systemic fibrosis (NSF) have been identified, primarily among patients with advanced kidney disease. Multiple studies have suggested an association between gadolinium-based contrast agents (GBCAs) and NSF. We performed a systematic review and meta-analysis to examine this potential association. METHODS A systematic review of st...

Nephrogenic systemic fibrosis (NSF) is a fibrosing disorder that may develop in patients who have advanced reduction in renal function. A causal relation between gadolinium (Gd(3+))-based contrast agents (Gd-CA) and NSF is probable and is supported by the accumulating data in the literature. From those data, the prevalence of NSF is seen to be significantly higher after exposure to gadodiamide ...

Peripheral vascular disease (PVD) has an age-adjusted prevalence of 12% in the United States, causes significant morbidity and is associated with excess cardiovascular mortality. Contrastenhanced magnetic resonance angiography (CE-MRA) often substitutes for the more invasive ―gold standard‖ procedure of digital subtraction angiography (DSA). Given the frequency of renal functional impairment in...