نتایج جستجو برای: nephroprotective activity

تعداد نتایج: 1134807  

Journal: :JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH 2019

Journal: :Indian Journal of Pharmaceutical and Biological Research 2020

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده علوم پایه 1389

چکیده : مقدمه : ابتلا به آترواسکلروز در بیماران دیابتی بیشتر از افراد سالم می باشد . هموسیستئین می تواند به عنوان یکی از عوامل خطرزای آترواسکلروز مطرح با شد . آنزیم لستین کلسترول آسیل ترنسفراز نقش مهمی را در پاک سازی کلسترول آزاد در بافت ها از طریق عملکرد hdl-c بر عهده دارد .هدف از این مطالعه تعیین سطح فعالیت لستین کلسترول آسیل ترنسفراز (lcat activity ) در بیماران دیابتی نوع 2 در مقایسه با افر...

Journal: :Phytomedicine plus 2021

Lead (Pb) is a toxic heavy metal that causes kidney injury and oxidative tissue damage. Current drugs to treat nephrotoxicity have multiple side-effects. Therefore, the development of novel therapeutic approaches urgently required. We investigated nephroprotective efficacy flaxseed lignan secoisolariciresinol diglucoside (SDG) against lead acetate (PbAc)-induced renal toxicity in rats. The acti...

2016
Venugopala Rao Konda Ruckmani Arunachalam Madhavi Eerike Ramesh Rao K Arun Kumar Radhakrishnan Lakshmipathy Prabhu Raghuraman Vinayak Meti Sobita Devi

The gravity of the impact of renal failure on human health is well known and as there is no specific pharmacotherapy for renal failure, the current study was undertaken to evaluate the effect of root extract of Azima tetracantha, an ancient medicinal plant used in Siddha and Ayurvedhic systems of medicine. The experiment was done in glycerol-induced acute renal failure in Wistar albino rats. Th...

Journal: :TEXILA INTERNATIONAL JOURNAL OF BASIC MEDICAL SCIENCES 2017

Journal: :Biology, Medicine & Natural Product Chemistry 2023

Hippocratea africana root used locally in the treatment of poisoning was investigated to confirm its antidotal potential rats. The extract (200-600 mg/kg) and fractions; dichloromethane (DCM) aqueous, 400 were evaluated for nephroprotective activity against doxorubicin-induced kidney injury Kidney function parameters, oxidative stress markers histology assess protective effect extract. fraction...

2015
Yu-Ju Ding Chiao-Yin Sun Chi-Chung Wen Yau-Hung Chen

The nephrotoxicity of aristolochic acid (AA) is well known, but information regarding the attenuation of AA-induced toxicity is limited. The aim of the present study was to study the nephroprotective effects of resveratrol (Resv) and ursolic acid (UA) in a zebrafish model. We used two transgenic lines, Tg(wt1b:EGFP) and Tg(gata1:DsRed), to evaluate the nephroprotective effects of Resv and UA by...

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