Whilst olfactory dysfunction has been reported in Korsakoff's Syndrome (KS) patients, the diagnostic implications of this have not been fully explored. KS can be difficult to diagnose because cognitive symptoms are similar to other diagnoses. For instance, patients with Frontal Lobe (FL) Syndrome may present with memory impairments that are similar to KS. Participants were given the Benton Visu...

PRIMARY OBJECTIVE The purpose was to evaluate a new self-reporting scale for assessment of mental fatigue and its usefulness in describing mental fatigue after neurological diseases and injuries. Mental fatigue is suggested to comprise a spectrum of items including sensory, emotional and cognitive symptoms. METHODS AND PROCEDURES Mental fatigue and related symptoms were measured with a self-a...

The association between scores on MMPI-2 scales and cognitive symptom validity test (SVT) failure was investigated in 127 criminal defendants evaluated for competency to stand trial, criminal responsibility, and drug dependence, and 141 personal injury and disability claimants. Results indicated that SVT failure was associated with exaggerated symptom presentation involving somatic complaints i...

Delinquency and criminality are common characteristics of FASD. It is widely believed that the pervasive neurobehavioral anomalies in FASD are the cause of criminality. These include impulsivity, lack of understanding of social cues and other dysfunction. We suggest an alternative hypothesis: There is strong association between excessive alcohol intake and criminality. There is also strong heri...

INTRODUCTION differentiating mild cognitive impairment (MCI) from normal cognition (NC) is difficult. The AB Cognitive Screen (ABCS) 135, sensitive in differentiating MCI from dementia, was modified to improve sensitivity and specificity, producing the quick mild cognitive impairment (Qmci) screen. OBJECTIVE this study compared the sensitivity and specificity of the Qmci with the Standardised...

The authors offer a framework for the assessment of psychological responses associated with exposure to early onset, multiple, or extended traumatic stressors. Six prominent and overlapping symptoms clusters are described: altered self-capacities, cognitive symptoms, mood disturbance, overdeveloped avoidance responses, somatoform distress, and posttraumatic stress. A strategy for the structured...

Brain calcifications may be present in a wide range of neuropsychiatric, infectious traumatic, neoplastic and endocrine conditions, associated with motor and cognitive symptoms. They are often considered "physiologic" or pathologic. OBJECTIVE To determine the prevalence of brain calcifications in a Brazilian cohort. METHODS 1898 consecutive patients underwent skull CTs, comprising 836 men a...

Previous studies have typically focused on the ability of cognitive symptom validity tests to identify cognitive symptom exaggeration in the context of head injury or memory loss. Few published studies have examined the detection of simulated attention-deficit/hyperactivity disorder (ADHD) or reading disorder (RD). The present study examined the accuracy of symptom validity measures in the dete...

Depression is a multidimensional condition encompassing affective, physiological, and cognitive symptoms. Although depression's high comorbidity with both epileptic and psychogenic nonepileptic seizures (ES and PNES) has been established, few studies have addressed whether the types of depressive symptoms experienced differ by seizure type (ES and PNES). This study compared the self-reported de...

Animal models of schizophrenia are important for research aimed at developing improved pharmacotherapies. In particular, the cognitive deficits of schizophrenia remain largely refractory to current medications and there is a need for improved medications. We discuss the pathophysiology of schizophrenia and in particular the possible mechanisms underlying the cognitive deficits. We review the cu...