The biogenic amine, histamine, has been shown to critically modulate inflammatory processes as well the properties of neurons and synapses in brain, is also implicated emergence neurodevelopmental disorders. Indeed, a reduction synthesis this neuromodulator associated with disorders Tourette’s syndrome obsessive-compulsive disorder, evidence that may be through disruption corticostriatal circui...

Neurotoxicity of organophosphate esters (OPEs) has been reported in toxicological studies, but epidemiological findings are limited. We aimed to assess the associations between prenatal OPE exposures and children’s neurodevelopment at 2 years old. measured urinary concentrations OPEs collected first third trimester from 184 pregnant women Wuhan, China. Childhood was assessed using Chinese revis...

BACKGROUND California sea lions have a large body burden of organochlorine pesticides, and over the last decade they have also been subject to domoic acid poisoning. Domoic acid poisoning, previously recognized in adult animals, is now viewed as a major cause of prenatal mortality. The appearance of a chronic juvenile domoic acid disease in the sea lions, characterized by behavioral abnormaliti...

INTRODUCTION Manganese (Mn) is an essential nutrient but higher exposure has been associated with poorer neurodevelopment in children. METHODS We measured Mn levels in prenatal (Mnpre) (n=197) and postnatal (Mnpost) dentin (n=193) from children's shed teeth using laser ablation inductively coupled plasma mass spectroscopy and examined the relationship with children's scores on the Mental Deve...

OBJECTIVES Limited evidence is available regarding the association between prenatal job strain and infant neurodevelopment. Most studies used stress indicators other than job strain to explain the relationship between prenatal maternal stress and child development. The objective of this study was to investigate the association between maternal job strain during pregnancy and neurodevelopment in...

BACKGROUND Intrauterine growth restriction (IUGR) affects 5-10% of all newborns and is associated with increased risk of memory, attention and anxiety problems in late childhood and adolescence. The neurostructural correlates of long-term abnormal neurodevelopment associated with IUGR are unknown. Thus, the aim of this study was to provide a comprehensive description of the long-term functional...

objectives: autism spectrum disorder (asd) is a group of neurodevelopment syndromes with impairments in social communications and restrictive or repetitive behaviors. neurofeedback is a new method that may regulate neuro and metabolic function in brain. this study is semi-experimental, with pre and post test.  methods: in 26 children with asd, 40 sessions of neurofeedback were done. brain waves...

Placental dysfunction leading to fetal growth restriction (FGR) is an important risk factor for neurodevelopmental delay. Recent observations clarify that FGR evolves prenatally from a preclinical phase of abnormal nutrient and endocrine milieu to a clinical phase that differs in characteristics in preterm and term pregnancies. Relating childhood neurodevelopment to these prenatal characteristi...

Optimal adaptation to changes that occur during pregnancy is essential prevent possible negative effects on maternal psychological health (such as stress or postpartum depression). In fact, an adequate the new life situation has implications subsequent offspring´s development. Thus, objective of present study was investigate potential association between levels personal growth and age with cogn...