CONTEXT The neurologic manifestations, laboratory findings, and outcome of patients with West Nile virus (WNV) infection have not been prospectively characterized. OBJECTIVE To describe prospectively the clinical and laboratory features and long-term outcome of patients with neurologic manifestations of WNV infection. DESIGN, SETTING, AND PARTICIPANTS From August 1 to September 2, 2002, a c...

Neuropsychiatry represents a field of medicine situated at the crossroads of neurology and psychiatry, and deals with the interface of behavioral phenomena driven by brain dysfunction. Psychiatric symptoms are highly prevalent in these conditions, are a major source of disability and diminished quality of life, and potentially represent the target of treatment interventions that stand to signif...

    Human T-cell lymphotropic virus (HTLV) types 1 and 2 belong to the Oncorna group of retroviridae, a large family of viruses, grouped initially by pathogenic features, but later revised on the basis of genome structure and nucleotide sequence. HTLV-I was the first discovered human retrovirus to be associated with a malignancy in 1980. The malignancy, first described by Uchiyama and co-worker...

We present a 19-year-old patient with hematologic and neurologic manifestations associated with Wilson's disease. Idiopathic thrombocytopenia was diagnosed in October 2009. Bone marrow aspiration was normal. Gradually her neurologic and psychiatric symptoms emerged, dysarthria, writing apraxia, learning difficulties, emotionalism and eventually dystonia of hands. The serum ceruloplasmin was low...

There are various neurologic manifestations of Multiple Myeloma (MM) seen either at presentation or as a complication of various antimyeloma agents administered during the course of the disease. These neurologic complications might occasionally be challenging to diagnose and treat. Peripheral nervous system is more commonly affected and peripheral neuropathy is the most common form of neurologi...

Six patients with various forms of retinitis pigmentosa who were misdiagnosed as having neurologic disease are presented. In five of the patients, visual field defects were misinterpreted as being secondary to a neurologic rather than a retinal problem. In two patients, optic nerve drusen, which accompanied the retinal degeneration, were mistaken for papilledema. Since the diagnosis of retiniti...

S ARCOIDOSIS is considered to be a granulomatous process that affects multiple systems. Neurologic symptoms develop in 1% to 2% of cases with Boeck’s sarcoid.’ Although the neurologic presentation has been uncommon, granulomas have been observed in up to 14% of patients with sarcoid at autopsy.’ The purpose of this presentation is to demonstrate the protean manifestations of sarcoidosis within ...

BACKGROUND Mutations in the glucocerebrosidase gene (GBA) result in Gaucher disease and can be associated with a phenotype characterized by adult-onset progressive neurologic deterioration and parkinsonism. OBJECTIVE To define the clinical and neurologic spectrum of parkinsonian manifestations associated with GBA mutations. Design, Setting, and Patients A prospective case series of 10 patient...

Dengue infection has been implicated as a cause of neurologic manifestations since the beginning of the 20th century. An enhanced surveillance system for encephalitis and aseptic meningitis developed by the Puerto Rico Department of Health in collaboration with the Dengue Branch, Centers for Disease Control and Prevention, identified eleven laboratory positive dengue patients presenting with ne...

lead poisoning has several clinical manifestations so the diagnosis may be troublesome. these manifestations consist of anemia, neurologic abnormalities, liver and biliary tract problems and abdominal pain. not only opium addiction, but also lead toxicity can cause biliary tract problems.when both etiologies occur at the same time, the diagnosis is difficult. a 46 year old opium addicted man wi...