Differentiation and maturation of myeloid cells is characterized by the sequential acquisition of two distinct cytoplasmic granule subsets, azurophil granules and specific granules. We recently showed the existence of a third granule subset, gelatinase granules. To investigate whether appearance of gelatinase granules marks a further step in maturation of myeloid cells beyond the appearance of ...

The results of published studies modern biomarkers used in the diagnosis acute kidney injury (AKI) were summarized. search was carried out PubMed/MEDLINE, Scopus, eLibrary databases. AKI occurs 10–15% all inpatients and 50% intensive care patients, affects economic aspects treatment rehabilitation. literature review allowed to draw conclusions about significant advantage new (cystatin C, neutro...