OBJECTIVES Alcea hyrcana Grossh (A. hyrcana Grossh) (malvacea), is native to northern of Iran. Many of the plants belonging to the genus Alcea are known to possess ethnomedical and biological properties. In this study, antioxidant activities of methanolic extracts of flower, seed and leaves of Alcea hyrcana Grossh were evaluated by various antioxidant assays. MATERIAL AND METHODS 1,1-diphenyl...

The aim of this study was to investigate whether green tea extract (GTE) has the protective effects on excess L-arginine induced toxicity in human mesangial cell. Human mesangial cells treated with L-arginine were cultured on Dulbecco's modified eagle medium in the presence and absence of inducible nitric oxide synthase (iNOS) inhibitor and GTE. The cell proliferation was determined by 3 (4,5-d...

Korean fir (Abies koreana Wilson) is traditionally used in folk medicine for its antibacterial, memory-enhancing, and anti-inflammatory properties. In this study, we evaluated the antioxidant skin-whitening effects of methanol ethanol extracts needles. The were tested their capacity using various assays, including radical scavenging (1,1-diphenyl-2-picrylhydrazyl, O2-, H2O2 NOž), SOD-like, ferr...

Purpose: To evaluate in vitro anti-oxidant and anti-neuro-inflammatory activities of Suaeda japonica extract (SJE) in lipopolysaccharide (LPS)-stimulated BV-2 microglial cells. Methods: 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay was used to study the antioxidant effects. 3-(4, 5-dimethylthiazol-2-yl)-2, 5diphenyl-tetrazolium bromide (MTT) assay was used to study cell viabil...

Objective: Terminalia arjuna is commonly known as Arjuna and widely used as cardioprotective agent in Indian traditional medicine. The present study was undertaken to evaluate the protective effect of ethanolic extract of T. arjuna bark (TAA) and its fractions, including dichloromethane (TAD), ethyl acetate (TAE), butanol (TAB) and water (TAW) against free radicals, protein oxidation and DNA da...

Purpose: To investigate the anti-oxidant and anti-neuroinflammatory effects of Salicornia bigelovii extract (SBE) in lipopolysaccharide (LPS)-stimulated BV-2 microglial cells. Methods: Anti-oxidant activity was measured using 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay. Cell viability was evaluated using 3-(4, 5-dimethylthiazol-2-yl)-2, 5diphenyltetrazolium bromide (MTT) ass...

Anogeissus latifolia is widely used in the Indian indigenous system of medicine and is reported to contain leucocyanidins and tannoid principles like ellagic acid and its derivatives. In view of its wide use and its chemical composition, this study was aimed at examining the antioxidant activity of the extract of A. latifolia. The extract was studied for total antioxidant capacity, hydrogen-don...

Introduction and Aim: Harnessing traditional knowledge of medicinal plants is important for the betterment mankind. We must safeguard from misuse by miscreants living in modern societies be available public domain use drug designing healthcare system. Since beginning recorded history, Indians have used as a source medicine, their cultural past incredibly rich. This study was conducted to evalua...

background: macrophages have important role in defense against herpes simplex virus type-1 (hsv-1). the present study was performed to determine the viability and nitric oxide (no) production by hsv-1 infected mouse peritoneal macrophages (him).   method: the viability of macrophages was evaluated using mtt reduction assay and the production of nitrite using griess method.   results: the abilit...

The aim of this study was to investigate the antioxidant activity using different in vitro assays and nitric oxide synthase activation property of crude water soluble polysaccharide from P. ostreatus. The polysaccharide was isolated by hot water extraction and physico-chemical investigation revealed that it contained high amount of carbohydrate (mostly β-glucan) and low amount of protein and ph...