The pentahaem enzyme cytochrome c nitrite reductase catalyses the reduction of nitrite to ammonia, a key reaction in the biological nitrogen cycle. The enzyme can also transform nitrogen monoxide and hydroxylamine, two potential bound reaction intermediates, into ammonia. Structural and mechanistic aspects of the multihaem enzyme are discussed in comparison with hydroxylamine oxidoreductase, a ...

Nitrite anion has been demonstrated to be a prodrug of nitric oxide (NO) with positive effects on tissue ischemia/reperfusion injury, cytoprotection, and vasodilation. However, effects of nitrite anion therapy for ischemic tissue vascular remodeling during diabetes remain unknown. We examined whether sodium nitrite therapy altered ischemic revascularization in BKS-Lepr(db/db) mice subjected to ...

Paracoccus pantotrophus cytochrome cd(1) nitrite reductase is isolated under aerobic conditions from anaerobically grown cells in an inactive form. This state requires reductive activation to make it catalytically competent for nitrite reduction. In this work, we discuss the methods of this reductive activation and its consequences for the cell.

398 Nitrate and nitrite Nitrate (NO 3 ) is found naturally in the environment and is an important plant nutrient. It is present at varying concentrations in all plants and is a part of the nitrogen cycle. Nitrite (NO 2 ) is not usually present in significant concentrations except in a reducing environment, as nitrate is the more stable oxidation state. It can be formed by the microbial reductio...

Nitrate and certain short chain nitrocompounds and nitro-oxy compounds are being investigated as dietary supplements to reduce economic and environmental costs associated with ruminal methane emissions. Thermodynamically, nitrate is a preferred electron acceptor in the rumen that consumes electrons at the expense of methanogenesis during dissimilatory reduction to an intermediate, nitrite, whic...

In this work; the optimum conditions of the differential pulse polarographic method conditions of the polarographic reduction of diphenylnitrosoamine which was occured by nitrite ion and diphenylamine in perchloric acidic medium and thiocyanate ion as catalyst, were determined. At these polarogram conditions, nitrite ion gave a maximum diffusion current at -0.56 V. The differential pulse polaro...