Purpose: Nanostructured lipid carriers (NLCs) composed of solid lipid and oil are a new generation of lipid nanoparticles which have exhibited some merits over traditional used lipid nanoparticles in fortifying food and beverages and nutraceuticals delivery systems such as liposomes and solid lipid nanoparticles. Methods: In this study, Precirol and Compritol as solid lipids, Miglyol and Octylo...

Objective: The current work involves formulation development of nanostructured lipid carrier (NLC) eperisone hydrochloride (EPE) using quality by design (QbD) approach.
 Materials and Methods: Initial screening solid liquid lipids was performed based on the Hansen solubility parameters EPE later confirmed saturation studies. optimum identified three-squared randomized full factorial design...

Abstract: Introduction: Formulation of a nano lipid carrier loaded hydrophilic gel corticosteroid, fluticasone propionate (FP) was investigated systemically with response surface model (RSM) for promising dermal delivery the drug. Objectives: To achieve better penetration drug and to overcome generally associated adverse reactions corticosteroids, present study, explored formulation evaluation ...

In summer 2001 a potassium lidar was installed near Longyearbyen (78 N) on the north polar island of Spitsbergen which is part of the archipelago Svalbard. At the same place a series of meteorological rockets (“falling spheres”, FS) were launched which gave temperatures from the lower thermosphere to the stratosphere. The potassium lidar is capable of detecting noctilucent clouds (NLCs) and of ...

The aim of this study was to understand the effect high shear homogenization (HSH) and ultrasonication (US) on physicochemical properties blank olanzapine loaded nanostructured lipid carriers (NLCs) along with their drug loading potential release profiles from formulated particles. NLCs were prepared different ratios Compritol Miglyol as solid liquid lipids, respectively, under changing HSH US ...

Objective: The aim of present study was to prepare triamcinolone acetonide (TA) loaded NLCs hydrogel for antipsoriatic activity. Methods: A Nanostructured lipid carrier (NLCs) prepared by using solvent diffusion and high pressure homogenization methods. dispersion characterized particle size, zeta potential, scanning electron microscopy (SEM), differential calorimetry, an in vitro release study...

The blood-brain barrier (BBB) and tumour (BBTB) pose a significant challenge to drug delivery brain tumours, including aggressive glioblastoma (GB). present study rationally designed functional nanostructured lipid carriers (NLC) tailor their BBB penetrating properties with high encapsulation of CNS negative chemotherapeutic docetaxel (DTX). We investigated the effect four liquid lipids, propyl...

Horizontal gene transfer (HGT) in food matrices has been investigated under conditions that favor exchange. However, the major challenge lies determining specific pertaining to adapted microbial pairs associated with matrix. HGT is primarily responsible for enhancing repertoire evolution and spread of antimicrobial resistance a target controlling pathogens public health concern ecosystems. In t...