Background: Allium jesdianum (AJ), as a plant in onion category, has antioxidant features. Moreover, γ-ray potentially generates oxidative stress living organisms. Objectives: In this study, the probable therapeutic effects of AJ on destruction pancreas tissue following were evaluated. Methods: Sixty-four mature NMRI mice (8 animals each group) assigned to eight groups follows: (1) Control; (2)...

Background: Leaves of Mangifera indica L or Lannea microcarpa Engl. & K. Krause are used in traditional medicine Burkina Faso to treat bacterial, parasitic metabolic diseases. Objective: The aim this study is evaluate the acute general toxicity, antioxidant potential and antibacterial activitiy leave’s aqueous extracts from L. use these plants motivated our choice lead scientific studies. Metho...

Background Aluminum (Al) is known to induce neurotoxicity in both humans and rodents. Recent evidence has indicated that the toxicity of Al Oxide (Al2O3) Nanoparticles (Al-NP), one most abundantly used engineered nanoparticles, far greater than itself. To date, however, no information available regarding effect Al-NP on stereological parameters hippocampus. In particular, studies have evaluated...

OBJECTIVE The effects of exposure to electromagnetic fields (EMF) on reproduction systems have been widely debated. In this study, we aimed to investigate whether low frequency EMF could ameliorate the in vitro fertilization success rate in Naval medical research institute (NMRI) Mice. MATERIALS AND METHODS In this randomized comparative animal study, ten NMRI mice were randomly divided into ...

BACKGROUND Several studies have demonstrated the derivation of multi- or pluripotent stem cells from testicular cells of both newborn and adult mice by a spontaneous conversion process, when these cells are cultured in vitro for an extended time. To obtain a better and robust derivation, we have attempted to identify small molecules (SMs) that induce reprogramming of testicular cells in culture...

background: over the past several years, mammals have been successfully cloned by either the splitting of an early stage embryo or nuclear transfer of adult somatic cells (nt) into oocytes. although it has been 15 years since the generation of the first cloned mammals from somatic cells by nt, the success rate for producing live offspring by this technique is low regardless of the cell type and...

disodium glycyrrhetinic acid hemiphthalaic (gap) was evaluated for developmental toxicity in pregnant nmri mice. gap was administered intrapcritoneally on days s, 9, 10, of gestation at doses of 0, 25, 50 and 75 mg/kg/dav. on gestation day of is, after operational delivery, the fetuses were examined for soft tissue, external and skeletal defects. increased absorptions, dead fetuses, and reduce ...

In a recent paper on in vivo proton MRS of mouse brain at 9.4 T, Tkáč et al. (1) reported high-quality single-voxel spectra of small volumes, but failed to accomplish a fair comparison with a previous study by Schwarcz et al. (2) at 2.35 T. Instead, the reader was left with the impression that proton MRS of mouse brain at low field strengths is of low value and is generally hampered by problems...

infertility is a relatively common problem among couples, and gossypol, a yellowishpigment detected in cottonseed, is one cause.adult nmri mice (25-35 gr) were used in this study. the animals were kept in standard conditionswith a dark and light cycle of 12:12, controlled humidity and temperature, food and water were availableadlibitium.gossypol was dissolved in ethanol and diluted by sunflower...

Background: The present study was carried out to investigate the possible protective effects of royal jelly (RJ) on oxymetholone (OXM)-induced oxidative liver injuries in mice. Methods: In total, 32 adult male NMRI mice were divided into four groups of eight mice each. Mice in groups 1 and 2 were orally administered 5 mg/kg/day OXM for 30 days. At the same time, mice in group 3 received RJ at a...