background: some studies  in recent  years showed  that carotid  intima-media   thickness  (imt),  indicator  of  the presence  of atherosclerosis,  was higher  in non-alcoholic fatty  liver disease  (nafld)  in comparison  with  normal subjects.  they concluded  that  nafld  patients  may  be resulted  in more cardiovascular events. hence, we aimed to study the association of nafld and ischemi...

INTRODUCTION Mitochondrial dysfunction plays a central role in the general pathogenesis of non-alcoholic fatty liver disease (NAFLD), increasing the risk of developing steatosis and subsequent hepatocellular inflammation. We aimed to assess hepatic mitochondrial function by a non-invasive (13)C-methionine breath test (MeBT) in patients with histologically proven NAFLD. METHODS 118 NAFLD-patie...

Non-alcoholic fatty liver disease (NAFLD) has become one of the top concerns for the practicing hepatogastroenterologist due to the obesity epidemic and it’s potential to progress to advanced liver disease which significantly impacts on overall and liver-related mortality. NAFLD may cause the liver to swell (steatohepatitis). An inflammation in liver may cause scarring (cirrhosis) over time and...

Non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease in the Western world, is tightly associated with obesity and metabolic syndrome. NAFLD entails an increased cardiometabolic and liver-related risk, the latter regarding almost exclusively non-alcoholic steatohepatitis (NASH), the progressive form of NAFLD. Pathogenetic models encompass altered hepatic lipid partiti...

Background: Non-alcoholic fatty liver disease (NAFLD) encompasses the entire spectrum of fatty liver disease in individuals without significant alcohol consumption and affects up to a third of the population in many developed countries. Approximately 10-30% of patients with NAFLD will progress to non-alcoholic steatohepatitis (NASH), which is associated with hepatocellular injury and inflammati...

Non-alcoholic fatty liver disease (NAFLD) is a chronic progressive liver disease, coupled with metabolic syndrome, which may progress to non-alcoholic steatohepatitis (NASH). Diabetes, obesity, hypertension, hypercholesterolemia, and hypertriglyceridemia are considered to be the most common causes leading to the incidence of NAFLD. It is assumed that the accumulation of lipid deposits in hepato...

AIM To assess how serum gamma-glutamyltransferase (GGT) fractions vary in patients with alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). METHODS Serum samples were obtained from 14 patients with biopsy-proven alcoholic liver diseases and 9 patients with biopsy proven non-alcoholic fatty liver disease. In addition to these biopsy-proven cases, 16 obese (body mass in...

Non-alcoholic fatty liver disease (NAFLD) is a complication of global prevalence occurring due to defective regulation of hepatic lipid metabolism. Currently, NAFLD is being viewed as an emerging epidemic by virtue of increase in obesity cases. Accumulation of excess fatty acid in the liver, leads to activation of an array of inflammatory signals, resulting in hepatic steatosis. Inadequately tr...

Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease in developed countries. Obesity is the most important risk factor for metabolic syndrome and NAFLD. Accumulated evidence has revealed that gut microbial compositional changes may be associated with more energy harvesting from the diet, which promotes increased fatty acid uptake from adipose tissue and shifts l...

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is one of the common diseases worldwide that not associated with alcohol consumption; it a group disorders caused by fat accumulation in liver. AIM: The research aims to assess levels serum sialoprotein, sclerostin, and osteocalcin men NAFLD. METHODS: current study was conducted Basra city, Iraq 2020, which includes 400 NAFLD, age ranges bet...