Micellar solubilization is a powerful alternative for dissolving hydrophobic compounds in aqueous environment. Fluorescence and absorption spectroscopy are the two techniques used to monitor the micellar solubilization studies of p-amino benzoic acid (PABA). PABA is an aromatic compound with acidic functional group, is non essential nutrient, used as a sunscreen. Externally, it prevents sunburn...

The solubilization of glucose and several related sugars in benzene solutions of rigorously purified phosphatidylcholine has been studied; the equilibrium degree of solubilization has been found to depend on the size of the sugar molecule relative to that of the lecithin micelle, and on the number and the acidity of its free hydroxyl groups. The uptake of glucose increased as the lecithin conce...

In this study, the solubilization of two organic dyes, Sudan I (1-Phenylazo-2-naphtol) and Quinizarin (1,4-Dihydroxyanthraquinone), was studied in the presence of different types of surfactants (2 polymerics, 2 nonionics, 2 anionic, and one cationic) using UV-Vis spectroscopy. The effects of temperature, pH and addition of different electrolytes (NaCl, Na2CO3, NaI, NaOH, NaSCN) on dye solubiliz...

The dataset presented here represents analysis supplied by the local proteomics core facility on samples submitted to it in support of the article "Assembly of proteasome subunits into non-canonical complexes in vivo" Hammack and Kusmierczyk (2016) [1]. This article provides the detailed protein contents of gel slices, cut from non-denaturing polyacrylamide gels, containing distinct protein com...

Inclusion bodies produced in Escherichia coli are composed of densely packed denatured protein molecules in the form of particles. Refolding of inclusion body proteins into bioactive forms is cumbersome, results in poor recovery and accounts for the major cost in production of recombinant proteins from E. coli. With new information available on the structure and function of protein aggregates i...

Pluronic/bile salt/phospholipid mixed micelles (Pluronic/BS/PS-MM) drug carrier system for solubilization hydrophobic drugs was developed. A typical hydrophobic compound, pyrene, was selected as a representative hydrophobic compound to model the hydrophobic drugs. Five Pluronics, F68, F88, F98, F108, and F127 with different PPO chain length were studied. CMC data and solubilization capacities w...