A difficulty in using diffusion models to predict large scale animal population dispersal is that individuals move differently based on local information (as opposed to gradients) in differing habitat types. This can be accommodated by using ecological diffusion. However, real environments are often spatially complex, limiting application of a direct approach. Homogenization for partial differe...

Objective(s): Ketotifen fumarate (KF) is a selective and noncompetitive histamine antagonist (H1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and conjunctivitis. The aim of this study was to formulate and improve an ophthalmic delivery system of KF.Ocular nanoparticles were prepared with the objective of reducing the frequency of administration and obtain...

Water-soluble AstaSana astaxanthin (AST) was loaded into 75/25 blend films made of polysaccharides (carboxymethyl cellulose (CMC), gum Arabic (GAR), starch sodium octenyl succinate (OSA), water-soluble soy (WSSP)) and gelatin (GEL) at levels 0.25, 0.5, 1%, respectively. Due to the presence granules in AST formulation, supplemented exhibited increased surface roughness as compared AST-free films...

Thermocompression was employed to prepare citric acid-crosslinked chitosan films with Aloe vera (AV) as bioactive compound. Films were easy handle and mechanical properties did not change the addition of AV up 10 wt%, although both TS EAB decreased for 15 wt% AV, indicating that high contents would hinder intermolecular interactions among formulation components. Maillard reaction occurred betwe...

Controlled drug release devices of pH-sensitive, complexing poly(acrylic acid-g-ethylene glycol) (P(AA-g-EG)) hydrogels were prepared by free radical solution UV polymerization. The effects of hydrogel composition, polymerization conditions and surrounding environment on theophylline release kinetics and drug transport mechanisms were evaluated in these P(AA-g-EG) polymer networks. Release stud...

objective(s): in this work, electrospun nanofibers were explored as drug delivery vehicles using tetracycline as a model drug.  nanocomposite fibers including chitosan (cs)/poly (ethylene oxide) (peo) and antibiotic were successfully prepared using electrospinning. cs blended with peo considering a weight ratio of (90/10), and then, nanofibrous samples were successfully electrospun from their a...

objective(s): pharmaceutical industries are leading to improved medications that can target diseases more effectively and precisely. researchers have intended to reformulate drugs so that they may be more safely used in human body. the more targeted a drug is, the lower its chance of triggering drug resistance, a cautionary concern surrounding the use of broad-spectrum antibiotics. the aim of t...

Objective: The objective of this study was to formulate and evaluate the Curcumin (CUR) encapsulated sodium alginate (SA)/badam gum (BG)/kaolin (KA) microbeads for controlled drug release studies.
 Methods: fabricated were characterized by fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), X-ray diffraction (X-RD), ele...

Nicotinic Acid (NA) is a cholesterol lowering agent used to treat dyslipidemia. Proanthocyanidins (PC) was selected as drug and encapsulation material in which the later has dual property of being polymer well agent. The NA with different concentrations carried out by solvent evaporation technique. encapsulated converted granules were then compressed into tablets wet granulation method. It subj...

objective(s): ketotifen fumarate (kf) is a selective and noncompetitive histamine antagonist (h1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and conjunctivitis. the aim of this study was to formulate and improve an ophthalmic delivery system of kf.ocular nanoparticles were prepared with the objective of reducing the frequency of administration and obtain...