BACKGROUND The mainstay of therapy for catecholaminergic polymorphic ventricular tachycardia (CPVT) is maximal doses of beta-blockers. However, although beta-blockers prevent exercise-induced ventricular tachycardia (VT), most patients continue to have ventricular ectopy during exercise, and some studies report high mortality rates despite beta-blockade. OBJECTIVE The purpose of this study wa...

Abstract Background A blunted heart rate reserve (HRR) during dobutamine stress echo (DSE) is an index of the altered cardiac sympathetic reserve, which frequently present in diabetes mellitus (DM) or chronic kidney disease (CKD). Aim To assess prognostic value HRR DSE. Methods We recruited 280 patients (mean age 62.9±13.1 years; 128 (45.7%) male; 28.2% on beta-blockers at time testing) who und...

BACKGROUND Beta blockers have been used widely in the treatment of hypertension and are recommended as first-line drugs in hypertension guidelines. However, a preliminary analysis has shown that atenolol is not very effective in hypertension. We aim to substantially enlarge the data on atenolol and analyse the effect of different beta blockers. METHODS The Cochrane Library and PubMed were sea...

OBJECTIVE A cancer diagnosis provokes significant levels of emotional distress, with intrusive thoughts being the most common manifestation among breast cancer survivors. Cancer-related intrusive thoughts can take the form of emotional memories, flashbacks, nightmares, and intrusive images. Emotional arousal after a severe life stressor prolongs adrenergic activation, which in turn may increase...

Single-dose administration of beta-adrenoceptor agonists produces bronchodilation and inhibits airway hyperresponsiveness (AHR), and is the standard treatment for the acute relief of asthma. However, chronic repetitive administration of beta-adrenoceptor agonists may increase AHR, airway inflammation, and risk of death. Based upon the paradigm shift that occurred with the use of beta-blockers i...

Because carvedilol is a unique vasodilating β blocker (BB) exerting antioxidant activity and pleiotropic effects, it was theorized that it may confer more potent beneficial effects on cardiovascular mortality and morbidity in acute myocardial infarction (AMI) and heart failure (HF) settings. A systematic review and meta-analysis was performed of randomized, controlled, direct-comparison trials ...

Objective: To ascertain the frequency of hypoglycemia in diabetic patients using beta blockers.Study Design: A descriptive cross-sectional study.Place and Duration Study: The study was conducted Department Nephrology Medicine, Lady Reading Hospital Peshawar, Pakistan, from 10th October 2021 to April 2022.Materials Methods: total number with 196, who were included this study. patients’ medical r...

AIMS Beta-blockers are the standard of care for the treatment of long QT syndrome (LQTS), and have been shown to reduce recurrent syncope and mortality in patients with type 1 LQTS (LQT1). Although beta-blockers have minimal effect on the resting corrected QT interval, their effect on the dynamics of the non-corrected QT interval is unknown, and may provide insight into their protective effects...

I n a recent large study, patients with non–small-cell lung cancer who added beta blockers to radiotherapy showed better overall survival, distant metastasis– free survival, and disease-free survival than those receiving radiation alone. In this 12-year retrospective study of 722 patients, 155 who took beta blockers for hypertension and heart disease survived for a mean of 23.7 months, compared...