نتایج جستجو برای: nonalcoholic steatohepatitis
تعداد نتایج: 13470 فیلتر نتایج به سال:
The importance of nonalcoholic steatohepatitis (NASH) was first recognized formally at a National Institutes of Health Consensus Symposium in December 1998. Since then, there has been a rapid growth of knowledge regarding nonalcoholic fatty liver disease (NAFLD) in children. The greatest advances have been made in the realms of awareness, diagnosis, and understanding of associated comorbidities...
Nonalcoholic fatty liver disease (NAFLD) refers to a spectrum of liver damage ranging from simple steatosis to nonalcoholic steatohepatitis, advanced fibrosis, and rarely, progression to cirrhosis. The pathogenesis of NAFLD is thought to be related to insulin resistance and oxidant stress. Truncal obesity, dyslipidema, hypertension, and hyperglycemia are strongly associated with NAFLD; therefor...
Nonalcoholic fatty liver disease (NAFLD) is already the most common liver disease in the Western world, where overweight or obese adults make up the growing majority. Its comparable impact in other regions, such as Asia, is increasingly being recognized. As we enter into an era of improving global hepatitis B vaccination coverage and effective therapies to either control or eradiate chronic vir...
In 1980, Ludwig et al. first reported patients of steatohepatitis who lacked a history of excessive alcohol consumption but showed liver histology resembling alcoholic hepatitis and progression to cirrhosis of the liver accompanied by inflammation and fibrosis. The development of nonalcoholic steatohepatitis (NASH) is associated with obesity, diabetes mellitus, insulin resistance, and hyperlipi...
As the hepatic manifestation of the metabolic syndrome, nonalcoholic fatty liver disease (NAFLD) has become the most common cause of asymptomatic liver enzyme elevations in Western nations. Although it is easy to diagnose NAFLD, a liver biopsy is currently required to diagnose nonalcoholic steatohepatitis (NASH). Patients with NASH are those at greatest risk of progression to cirrhosis and, thu...
The discovery of metabolite-phenotype associations may highlight candidate biomarkers and metabolic pathways altered in disease states. We sought to identify novel metabolites associated with obesity and one of its major complications, nonalcoholic fatty liver disease (NAFLD), using a liquid chromatography-tandem mass spectrometry method. In 997 individuals in Framingham Heart Study Generation ...
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