نتایج جستجو برای: nonclinical services
تعداد نتایج: 302306 فیلتر نتایج به سال:
This paper presents a new approach for network meta-analysis that combines multivariate con9 fidence distributions (CDs). Network meta-analysis generalizes the traditional meta-analysis of 10 pairwise comparisons to synthesizing studies for multiple treatment comparisons, and supports 11 inference on all treatments in the network simultaneously. It can often strengthen inference on 12 a pairwis...
BACKGROUND AND PURPOSE Qualitative studies are increasingly used to investigate social processes and phenomena influencing health behaviors and service provision. We aimed to identify the scope of published qualitative studies of stroke, consider their relevance to development and delivery of services for people with stroke, and make recommendations for future work. METHODS Literature review ...
Atacicept, a soluble recombinant fusion protein of the human immunoglobulin (Ig) G(1) Fc and the extracellular domain of the human transmembrane activator and calcium modulator and cyclophylin ligand interactor receptor, acts as an antagonist of both B lymphocyte stimulator and a proliferating-inducing ligand. Here we determined the nonclinical safety, pharmacokinetics and pharmacodynamics of a...
Book Review: Toxicologic Pathology, Nonclinical Safety Assessment, Edited by Sahota PS, Popp JA, Hardisty JF, and Gopinath C, CRC Press, 1,015 pages, 158 color illustrations, 43 tables, 2013. Hardback version (ISBN 9781-4398-7210-9; $259.95) and ebook version (ISBN 978-14398-7212-3; $181.97). Katsuhiko Yoshizawa, DVM, MS, PhD, DJSTP, DJCVP, DJST, FIATP Kansai Medical University Department of Pa...
The failure of current Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccines, given to neonates to protect against adult tuberculosis and the risk of using these live vaccines in HIV-infected infants, has emphasized the need for generating new, more efficacious and safer replacement vaccines. With the availability of genetic techniques for constructing recombinant BCG (rBCG) strains contai...
The white paper Working for Patients represents the cumulative achievement ofthe most radical free market proposals for the NHS since the government came into office in 1979.2 Change has occurred in a step wise fashion through several measures designed to alter the cultural norms of the health service. Increased local accountability, quicker decision making,3 the identification of key decision ...
Background & Aims: The aim of the current study was to investigate the relationship between thought fusion beliefs and thought control strategies with obsessive-compulsive symptoms in nonclinical population. Materials & Method: This study was conducted on 420 students of Tabriz University. All participants completed thought fusion instrument (TFI), the thought control questionnaire (TCQ) and M...
The label 'chronic fatigue syndrome' (CFS) has persisted for many years because of the lack of knowledge of the aetiological agents and the disease process. In view of more recent research and clinical experience that strongly point to widespread inflammation and multisystemic neuropathology, it is more appropriate and correct to use the term 'myalgic encephalomyelitis' (ME) because it indicate...
The probability law of a stochastic process is usually specified by giving all the finitedimensional distributions (f.d.d.’s). Let {X(t) : t ≥ 0} be a stochastic process; i.e., a collection of random variables indexed by the parameter t, which is usually thought of as time. Then the f.d.d.’s of this stochastic process are the collection of k-dimensional probability distributions of the random v...
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