Chronic sinusitis is a common disease that encompasses a number of syndromes that are characterized by sinonasal mucosal inflammation. Chronic sinusitis can be defined as two or more of the following symptoms lasting for more than 12 consecutive weeks: discolored rhinorrhea, postnasal drip, nasal obstruction, facial pressure or pain, or decreased sense of smell. Chronic sinusitis is further cla...

health care impact. This review focuses on factors contributing to sinusitis pathogenesis and chronicity, including anatomic factors, disturbances in mucociliary clearance, microbial pathogens, and inflammatory factors. A distinction is made between “infectious” and “noninfectious” types of inflammation in chronic sinusitis. The inflammatory characteristics of noninfectious inflammation are rev...

Introduction Percutaneous tracheostomy is one of the most commonly operative procedures performed in Intensive Care Unit (ICU) patients [1]. Ciaglia Blue Rhino technique (CBR) is used in our ICU. In our clinical practice we sometimes encountered difficulties in doing initial dilatation of the soft tissue and tracheal wall with the Blue Rhino dilator: it occurs expecially in young or obese patie...

Piwi-interacting RNAs (piRNAs) silence transposons and maintain genome integrity during germline development. In Drosophila, transposon-rich heterochromatic clusters encode piRNAs either on both genomic strands (dual-strand clusters) or predominantly one genomic strand (uni-strand clusters). Primary piRNAs derived from these clusters are proposed to drive a ping-pong amplification cycle catalyz...

piRNAs silence transposons during germline development. In Drosophila, transcripts from heterochromatic clusters are processed into primary piRNAs in the perinuclear nuage. The nuclear DEAD box protein UAP56 has been previously implicated in mRNA splicing and export, whereas the DEAD box protein Vasa has an established role in piRNA production and localizes to nuage with the piRNA binding PIWI ...

The focus of our rhinoceros research has been the characterization of basic reproductive biology by ultrasound and its application to captive management of these endangered species, work intricately dependent upon a dedicated and collaborative animal care and health team. Our rhino care and research objectives are facilitated bv a rhino internship position created to help with ongoing reproduct...

Background: Allergic fungal sinusitis is a non-invasive disease, and accounts for approximately 6-8% of all chronic sinusitis requiring surgical intervention. As the treatment and prognosis of these disorders vary significantly, it is extremely important to recognize allergic fugal sinusitis and differentiate it from chronic sinusitis of bacterial and fungal origin. This prospective study evalu...

<p class="abstract">In the midst of severe acute respiratory syndrome coronavirus 2 (SARS COV-2) pandemic, victims are acquiring secondary infections like mucormycosis. Rhinocerebral mucormycosis (ROCM), is most prevalent form and an invasive, opportunistic fungal infection that typically affects immunocompromised patients. It exhibits a pronounced propensity to invade blood arteries, res...