Volume 22, Issue 2 November 2006 1 Overactive bladder (OAB) is a chronic and potentially debilitating condition that affects approximately 16% of the adult population in the U.S. and Europe. According to the National Overactive Bladder Evaluation (NOBLE) program, an estimated 34 million Americans have symptoms of OAB. Overactive bladder is a common condition in both men and women of all ages, b...

On the morning of Oct. 5, President Bush and his education secretary, Margaret Spellings, paid a visit, along with camera crews from CNN and Fox News, to Friendship-Woodridge Elementary and Middle Campus, a charter public school in Washington. The president dropped in on two classrooms, where he asked the students, almost all of whom were African-American and poor, if they were planning to go t...

Classically, the study of knots and links has proceeded topologically looking for features of knotted curves which depend only on their knot class. Recently there has been an increased interest in geometric knot theory, which attempts to measure geometric properties of a particular knotted curve and relate these to its knot type. Questions about the geometry of knots not only have intrinsic mat...

Gardi, J., F. Obál, Jr., J. Fang, J. Zhang, and J. M. Krueger. Diurnal variations and sleep deprivation-induced changes in rat hypothalamic GHRH and somatostatin contents. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1339–R1344, 1999.—Previous reports indicate that hypothalamic growth hormone-releasing hormone (GHRH) promotes sleep and is involved in sleep regulation. The ai...