Neuropathic pain (NPP) is intolerable, persistent, and specific type of long-term pain. It is considered to be a direct consequence of pathological changes affecting the somatosensory system and can be debilitating for affected patients. Despite recent progress and growing interest in understanding the pathogenesis of the disease, NPP still presents a major diagnostic and therapeutic challenge....

Neuropathic pain (NPP) is the main culprit among chronic pains affecting the normal life of patients. Procaine is a frequently-used local anesthesia with multiple efficacies in various diseases. However, its role in modulating NPP has not been reported yet. This study aims at uncovering the role of procaine in NPP. Rats were pretreated with procaine by intrathecal injection. Then NPP rat model ...

Biosphere plays an important role in the climate system, controlling the cycle of carbon. Additionally, the activity of ecosystems is particularly sensitive to climate variability (Ciais et al., 2003, Gouveia et al., 2008). The regional changes observed in temperature, radiation and precipitation in recent decades seems to have caused an increase in global Net Primary Productivity (NNP), increa...

Five experiments (Exp.) were conducted to determine the effects of phytase on growth performance and intestinal transit time in chicks fed nutritionally adequate diets and diets deficient in Ca and nonphytate P (nPP). In Exp. 1 and 2, chicks were fed a nutritionally adequate diet from 0 to 6 d or from 0 to 4 d posthatching; assay periods were 8 or 10 d; average initial BW were 98 or 79 g; and a...

In December 2014, a group of Australian financial institutions announced that funding had been secured for the next phase of the New Payments Platform (NPP), which will provide the capability for Australian consumers and businesses to make and receive payments in near to real time. The NPP is one example of a fast retail payment system, a number of which have been implemented in other countries...

Hydrogen peroxide (H2O2) detection in biological systems is of significant importance, which act as critical second messenger in fundamental biological processes. Here, we report on a chemoselective fluorescent naphthylimide peroxide probe (NPP) for the H2O2 detection in vitro and in vivo. NPP is a phenylboronic acid-caged chromophore that selectively responds to H2O2 through a self-immolate me...

The Dodewaard NPP was shut down in 1997 and is now in the decommissioning phase. All spent fuel has been removed from the plant and transferred to Sellafield, in the United Kingdom, for reprocessing. The last shipment of spent fuel from Dodewaard was made in April 2003. In May 2002 a license was granted to GKN, the operator of the NPP Dodewaard, to bring and keep the plant in a safe enclosure. ...

An NPP system consists of three important components: the machine system, operators, and MMI. Through the MMI, operators monitor and control the plant system. The cognitive model of NPP operators has become a target of modeling by cognitive engineers due to their work environment: complex, uncertain, and safe critical. We suggested the contextual model for the cognitive behavior of NPP operator...

Musilova A., Lichovnikova M., Kupcikova L., Anderle V. (2017): Effect of suboptimal levels of non-phytate phosphorus and exogenous phytase on precaecal digestibility of phosphorus and calcium in laying hens. Czech J. Anim. Sci., 62, 473–481. The precaecal digestibility of phosphorus and calcium in laying hens was evaluated at two dietary levels of non-phytate phosphorus (NPP; 1.58 and 2.03 g/kg...