Complement-fixing (CF) antibody-positive sera from hamsters bearing adenovirus type 12 (Ad. 12)-induced tumors revealed specific immunofluorescent stainable antigens in essentially all Ad. 12 hamster tumor cells. The antigens were primarily in the form of cytoplasmic flecks; less frequent staining was seen as nuclear flecks or homogeneous staining of nucleus and cytoplasm of a small proportion ...

Chromosomal nonhistone protein:DNA complexes prepared from synchronized HeLa cells were used to immunize white rabbits. The antisera reacted specifically in complement fixation tests with chromatins isolated from HeLa cells and not with those from a number of other human and animal tissues. Specificity to this cell type was also demonstrated by immunocytochemical reaction. Both immunochemical t...

Purpose Systemic lupus erythematosus (SLE) is characterized by the production of autoantibodies directed against many highly-conserved nuclear antigens. 15% of SLE patients develop disease in childhood or adolescence, and pediatric (pSLE) patients often have more severe disease onset and organ system involvement. Antigen microarray technology allows the comprehensive analysis of autoantibodies ...

apoptosis, or active cell death, is a specific mode of cell death, which is characterized by morphological changes such as chromatin condensation, fragmentation of the nucleus, cytoplasmic retraction and appearance of apoptotic bodies' containing apparently intact organelles. apoptosis occurs in physiological conditions as a regulatory mechanism of tissue growth, where cell proliferation is bal...

by immunizing mice with killed whole bacterial cells of brucella abortus s (99), a panel of six hybridomas producing monoclonal antibodies (mab) specific for the surface antigens of this bacterium were produced. elisa was used to screen the hybridoma supernatants. immunoblots of the cell extract indicated that three mab were specific for s-lps (ba-1, ba-2, ba-3) and three others were reactive w...

background: ornithobilharziosis as one of the parasitic infections may give rise to serious economic problems in animal husbandry. the aim of the study was to prepare and compare the somatic and excretory-secretory (es) antigens of o. tur­kestanicum in gel diffusion test. methods: excretory-secretory (es) and somatic antigens of ornithobilharzia turkestanicum were prepared from collected worms ...

psychological or behavioral interventions that attenuate the effects of stress may be useful in promoting immunocompetence and delaying hiv disease progression and cd4 count level. mindfulness-based stress reduction (mbsr) is a behavioral intervention that has as its foundation the practice of insight-oriented (or mindfulness) meditation. in this study, we examined the effects of mbsr upon psyc...

background and objective: the outcome of hepatitis b virus (hbv) infection may be influenced by host factors like human leukocyte antigen (hla). we have investigated hla-a and drb1 alleles in patients with persistent hepatitis b infection compared to subjects who had spontaneously recovered from hbv infection. to complete the findings of this study we performed another survey in certain hla all...

extramedullary plasmacytoma is a rare neoplasm characterized by monoclonal proliferation of plasma cells. most lesions occur in the head and neck, primarily in the upper aerodigestive tract. the nasal cavity and nasal septum are the most common sites of occurrence. in this report, three patients admitted in our clinic with history of nasal obstruction and/or epistaxis. patients were diagnosed w...