The transport of macromolecules into the nucleus is mediated by soluble cellular receptors of the importin β superfamily and requires the Ran-GTPase cycle. Several studies have provided evidence that there are exceptions to this canonical nuclear import pathway. Here, we report a new unconventional nuclear import mechanism exploited by the baculovirus Autographa californica multiple nucleopolyh...

Two types of propulsion systems-the hand rim (HR) and the arm crank (AC)-are commonly used in wheelchair ambulation. The purpose of this study was to investigate the physiological response of the two propulsion systems under actual locomotive condition by the actual users. The energetics of locomotion manual wheelchair (HR propulsion) and arm-propelled three-wheeled chairs (AC-propelled) at the...

As CubeSats grow in both numbers and capability, the need to extend their reach with integrated propulsion systems is becoming clear. A water-electrolysis propulsion system for 3U CubeSats is proposed that could fill the gap in the available propulsion systems at this scale. Combining the advantages of electric propulsion with those of chemical rockets, the system is safe both to handle and to ...

Laboratory-based simulators afford many advantages for studying physiology and biomechanics; however, they may not perfectly mimic wheelchair propulsion over natural surfaces. The goal of this study was to compare kinetic and temporal parameters between propulsion overground on a tile surface and on a dynamometer. Twenty-four experienced manual wheelchair users propelled at a self-selected spee...

This project was an experiment on the feasibility of superconductorbased maglev trains. Two classmates, Kyle Tessier-Lavigne and Michael Stern, and I worked in conjunction to produce a magnetic track, levitating train car, and propulsion system. This paper focuses on my part of the project, the propulsion system. The propulsion system is similar to a linear motor, with a row of solenoids attrac...