different research groups have extensively studied the associations of cytokine gene polymorphisms in different diseases. the role of cytokines gene polymorphisms in multiple sclerosis (ms), as a chronic immune-mediated neurodegenerative disease, has been previously reported in the various populations. for determining pro-inflammatory cytokine gene polymorphisms, 100 relapsing remitting multipl...

Introduction: E-selectin and ICAM-1 are cellular adhesion molecules that play important roles in the pathogenesis of Sickle Cell Disease (SCD), especially vaso-occlusion process. Numerous studies reported single nucleotide polymorphisms genes may be associated with clinical expression several diseases. However, no evidence exists regarding association SCD. Objectives: Investigate E-selectins (S...