‘‘Sixteen years as a general practitioner [GP] showed me that the prevailing biomedical reductionist model fails to address the complexity of human experience and psychosomatic illness that daily practice brings up, and for which I was not trained. Even at the purely physical level, there are huge gaps in conventional training with virtually no training in musculoskeletal medicine (a huge compo...

Understanding the determinants of animal abundance has become more vital as ecologists are increasingly asked to apply their knowledge to the construction of informed management plans. However, there are few general models are available to explain variation in abundance. Some notable exceptions are studies of folivorous primates, in which the protein-to-fiber ratio of foods has been shown to pr...

I address and explain the increased risk of adverse effects from nutrients by using the paradigm of hormesis, the biological and toxicological concept that small quantities have opposite effects from large quantities. To provide necessary background, I categorize, depict, discuss, and contrast hormetic and other dose-response relations. I review some of the different hormetic mechanisms that ot...

Lentinula edodes is a macrofungus with great potential for therapeutic applications and serves as a model for investigating functional fungi properties and isolating pure compounds for pharmaceutical use. Mushrooms have a great nutritional value and present medicinal molecules including polysaccharides, terpenoids, sterols and lipids, that participate actively in several human disorders and mod...

(2015) Nutrigenomic profiling of transcriptional processes affected in liver and distal intestine in response to a soybean meal-induced nutritional stress in Atlantic salmon (Salmo salar), Comparative Biochemistry and Physiology-Part D: Genomics and Proteomics, 15, pp. 1-11. Abstract 17 The aim of the present study was to generate an experimental model to characterize the 18 nutrigenomic profil...

PURPOSE Our objectives were to assess the performance of the 5-Colour nutrition label (5-CNL) front-of-pack nutrition label based on the Food Standards Agency nutrient profiling system to discriminate nutritional quality of foods currently on the market in France and its consistency with French nutritional recommendations. METHODS Nutritional composition of 7777 foods available on the French ...