Only 30% of alcoholics develop liver disease (ALD) suggesting that additional factors are needed. Endotoxin is one such factor, but its etiology is unclear. Since the gut is the main source of endotoxin, we sought to determine whether an increase in intestinal permeability (leaky gut) is required for alcohol-induced endotoxemia and liver injury and whether the gut leakiness is preventable. For ...

Concentrations of selected macro minerals (Ca, P, Na, K, and Mg) were determined from coolseason annual grass pasture forages over four consecutive late fall-winter-spring grazing seasons (2001-2005). Forage samples were taken from eight experimental pastures used in beef cattle grazing trials. Two, 2-yr experiments were conducted; animal and pasture data were reported previously (Myer and Blou...

Celiac disease (CD) is a life-long autoimmune condition affecting the small intestine of genetically susceptible individuals. Gluten is one of the offending inducers of the disease, with structurally related molecules found in barley, rye, and oats, where the offending peptides are called avenins. Avoiding toxic prolamins is the only established therapy but most patients have compliance difficu...

The impact of soil compaction on soybean root growth and grain yield can be alleviated by the presence biopores channels in profile. We hypothesize that cover crops (ruzigrass oats) are better than (wheat maize) to reduce physical limitation growth. aimed identify which precrops have higher potential mechanical water stresses resulting from desegregation, enhance (Glycine max L) an Oxisol (Rhod...

The human organic anion and cation transporters are classified within two SLC superfamilies. Superfamily SLCO (formerly SLC21A) consists of organic anion transporting polypeptides (OATPs), while the organic anion transporters (OATs) and the organic cation transporters (OCTs) are classified in the SLC22A superfamily. Individual members of each superfamily are expressed in essentially every epith...

Oats (Avena sativa L.) have been used as livestock and human foods since ancient times. It is a good source of many active phytocompounds which exhibit antiinflammatory, anti-oxidant and anti-colon cancer activities. In the present study, an insilico approach was followed to identify the potential phytocompounds of oats against anticolon cancer. Fourteen phytocompounds of oats were selected as ...

Drugs and xenobiotics bind to plasma proteins with varying degrees of affinity, and the amount of binding has a direct effect on free drug concentration and subsequent pharmacokinetics. Multiple active and facilitative transport systems regulate the excretion of anionic compounds from the blood in excretory and barrier tissues. Assumptions are made about in vivo substrate affinity and route of ...

A growing body of evidence suggests that a majority of people with celiac disease and on a gluten-free diet can safely consume pure oats in moderate amounts; however, previous studies have indicated that the commercial oat supply in other countries, and in Canada to some extent, is contaminated with other grains. This study has confirmed that the commercial oat supply in Canada is heavily conta...

Avenanthramides are unique components of oats (Avena sativa L.) that are described as phytoalexins and that have potential health promoting properties. The objectives of this study were to examine the avenanthramide contents and the activity of the avenanthramide biosynthetic enzyme hydroxycinnamoyl-CoA:hydroxyanthranilate N-hydroxycinnamoyl transferase (HHT) in spikelets and leaves of developi...