In recent years, scheduling optimization has been utilized in production systems. To construct a suitable mathematical model of problem, modeling techniques that can automatically select an appropriate objective function from historical data are necessary. This paper presents two methods to estimate weighting factors the problem data, given information operation time and setup costs. We propose...

This paper describes and demonstrates a new and highly innovative technique that identifies an approximation of the entire bounding surface of the feasible objective region directly, including deep concavities, disconnected regions and the edges of interior holes in the feasible areas. The Pareto front is a subset of the surface of the objective boundary and can be extracted easily. Importantly...

This paper introduces a context-oriented component-based application MDA (COCA-MDA) that modularizes the application’s context-dependent behaviour into context-oriented components. The components separate the application’s functional concerns from the extra-functional concerns. The application is organized into two casually connected layers: the base layer, which provides the application’s core...

The increase in the scale of preparative chromatographic processes for biopharmaceutical applications now necessitates the development of effective optimization strategies for large-scale processes in a manufacturing setting. The current state of the art for optimization of preparative chromatography has been limited to single objective functions. Further, there is a lack of understanding of wh...