Purpose. Ocular trauma with retained foreign body is an important cause of visual impairment in working-age population. Clinical status impacts on the timing and planning of surgery. In the last year small gauge vitrectomy has become safer and more efficient, extending the range of pathologies successfully treated. Aims. To evaluate the safety and outcomes in patients with open eye injury with ...

It is hypothesized that the striate cortex is concerned with, among other things, removing binocular correlations in the inputs. This theory is applied to explain the diierent ocular dominance column (ODC) formations observed after visual developments under strabismus, excessive binocular correlations, normal environment, and monocular deprivation. These ODC formations are shown to be consequen...

background: the pelger-huet anomaly dominantly is a rare and benign inherited defect of terminal neutrophil differentiation. although neutrophil migration may be minimally impaired, granulocytes function is otherwise normal association abnormalities such as ocular, musculoskeletal are reported very rare. case: an eight year-old boy with good consciousness but severe muscular atrophia and diffic...

purpose : to report a rare case of large vascularized astrocytoma on optic disc. case report : a 12-year-old boy with history of decreased vision in the left eye since 5-6 months ago was referred to the ocular oncology service at rassoul akram hospital with provisional diagnosis of retinoblastoma. on examination, visual acuity was counting fingers at 50 cm, and a 3+ relative afferent pupillary ...

ALTHOUGH diplopia resulting from head injury is more usually due to a lesion of one of the ocular motor nerves, it may be caused by direct injury to the orbit. Sometimes damage occurs to one or more of the extrinsic ocular muscles, especially the obliques, because of their attachments to the bone in the anterior part of the orbit, but more frequently the injury brings about an alteration in the...

BACKGROUND Neurological and/or neuropsychological damages are important complications of cardiosurgical interventions. This study determined if the timing of the electroretinographic (ERG) ocular exam can assess intraoperative brain damage of patients supported by extracorporeal circulation (ECC) during cardiosurgical interventions. MATERIALS AND METHODS The authors illustrate an ERG techniqu...

Poor dark adaptation is a not uncommon symptom and may occur in a wide variety of diseases but its occurrence in one eye only is far less frequent. When it occurs unilaterally, an obvious ocular disease is generally present to account for it and visual functions other than that of dark adaptation are also depressed. Some subjects with poor dark adaptation may have no demonstrable ocular lesion ...

The lacrimal gland has a multifaceted role in maintaining a homeostatic microenvironment for a healthy ocular surface via tear secretion. Dry-eye disease, which is caused by lacrimal gland dysfunction, is one of the most prevalent eye diseases that cause corneal epithelial damage and results in significant loss of vision and a reduction in the quality of life. Here we demonstrate orthotopic tra...

Amyloid-β (Aβ)-induced changes in synaptic function in experimental models of Alzheimer's disease (AD) suggest that Aβ generation and accumulation may affect fundamental mechanisms of synaptic plasticity. To test this hypothesis, we examined the effect of APP overexpression on a well characterized, in vivo, developmental model of systems-level plasticity, ocular dominance plasticity. Following ...

Ocular coloboma (OC) is a defect in optic fissure closure and is a common cause of severe congenital visual impairment. Bilateral OC is primarily genetically determined and shows marked locus heterogeneity. Whole-exome sequencing (WES) was used to analyze 12 trios (child affected with OC and both unaffected parents). This identified de novo mutations in 10 different genes in eight probands. Thr...