Puroose Recurrent ocular toxoplasmosis is a major cause of blindness throughout the world. However, the pathogenetic mechanisms of reactivation of latent Toxoplasma gondii (T. gondii) infections are still unknqwn. An important question is whether the recurrent focal inflammatory responses in the retina are primarily directed against the parasite itself or whether autoimmune mechanisms play a ro...

Puroose Recurrent ocular toxoplasmosis is a major cause of blindness throughout the world. However, the pathogenetic mechanisms of reactivation of latent Toxoplasma gondii (T. gondii) infections are still unknqwn. An important question is whether the recurrent focal inflammatory responses in the retina are primarily directed against the parasite itself or whether autoimmune mechanisms play a ro...

Toxoplasma gondii is an extremely successful opportunistic parasite which infects approximately one third of the human population worldwide. The impact of this parasite on human health becomes particularly manifest in congenital damage with infection and subsequent inflammation of neuronal tissues including the retina. Although advances in our understanding could be achieved in ocular toxoplasm...

Infection with Toxoplasma gondii is acquired through consumption of undercooked infected meat, or by uptake of cat-shed oocysts. Although congenital toxoplasmosis is generally considered to contribute most to the disease burden of T. gondii, ocular disease from acquired infection was recently shown to add substantially to the burden. In addition, toxoplasmosis in immune-compromised individuals ...

Puroose Recurrent ocular toxoplasmosis is a major cause of blindness throughout the world. However, the pathogenetic mechanisms of reactivation of latent Toxoplasma gondii (T. gondii) infections are still unknqwn. An important question is whether the recurrent focal inflammatory responses in the retina are primarily directed against the parasite itself or whether autoimmune mechanisms play a ro...