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OBJECTIVES To analyse the effects of rosiglitazone administered at different times on neointimal formation in hypercholesterolemic rabbits following vascular injury. METHODS Thirty-nine rabbits on a hypercholesterolemic diet were included. The animals underwent balloon catheter injury to the right iliac artery on day 14. They were divided into three groups as follows: control group, 13 rabbit...
ABST RACT The objective of this immunohistochemical study was to examine the expression of caspase-3,-5,-7, and -9 in sheep pox lesions in 15 naturally infected crossbred merino lambs. Sheep pox was diagnosed based on typical gross and histopathological lesions in the skin and visceral organs that were evaluated pathologically and immunohistochemically. Macroscopically, lesions were observed in...
NO has several putative atheroprotective properties but its precursor, L-arginine, and inhibitors of its synthesis have had inconsistent effects on the extent of experimental atherosclerosis in rabbits. The location and character of experimental atherosclerosis differ between immature and mature rabbits; both phenomena have been attributed to changes with age in the NO pathway. We investigated ...
BACKGROUND AND PURPOSE Chronic simulated snoring was induced in rabbits to determine the impact of snoring on the development of atherosclerosis. METHODS The pressure wave of induced snoring at the carotid bifurcation of rabbits was acquired by gently pressing the airway. This wave was then simulated using custom-made mechanical devices. Twelve rabbits were used in this study, seven of which ...
The 4th century BC marks the main entrance of Celtic populations in northern Italy. Their arrival has been suggested based on the presence of Celtic customs in Etruscan mortuary contexts, yet up to now few bioarchaeological data have been examined to support or reject the arrival of these newcomers. Here we use strontium isotopes, non-metric dental traits and funerary patterns to unravel the bi...
Recent observations from PAMELA, FERMI, and ATIC point to a new source of high energy cosmic rays. If these signals are due to annihilating dark matter (DM), the annihilation cross section in the present day must be substantially larger than that necessary for thermal freeze-out in the early universe. A new force, mediated by a particle of mass Oð100 MeVÞ, leading to a velocity-dependent annihi...
Introduction: [Cu]diacetyl-bis(N-methylthiosemicarbazone) ([Cu]ATSM) is a well-established hypoxia imaging tracer with reproducible production and significant specifity. In this work the high yield production and quality control as well as imaging studies in healthy rabbits is reported. Methods: Copper-64 produced via the Zn(p,n)Cu nuclear reaction (30 MeV protons at 180 μA) was used for the p...
From a public health perspective the disease of smallpox was officially declared eradicated in 1980 – the result of a successful global initiative led by the World Health Organization (WHO), the first and to date only success against a disease in humans. The world could celebrate its freedom from a dreaded disease. Much of the literature about the history of smallpox – a disease that has fascin...
Three basic postulates for Quantum Theory are proposed, namely the Probability, Maximum-Speed and Hilbert-Space postulates. Subsequently we show how these postulates give rise to well-known and widely used quantum results, as the probability rule and the linearity of quantum evolution. The suggested postulates also enables us to criticize EPR elements of reality under the Special Relativity phi...
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