Cumulative evidence suggests that neural network formation requires an ingenious regulation of the attractive and repulsive responses of growing axons to guidance cues. We examined the role of intracellular protein kinase A (PKA) signaling in the axonal pathfinding of olfactory sensory neurons in transparent zebrafish embryos. Microinjection of an olfactory marker protein gene promoter-driven d...

According to the recent researches on multimodal interfaces, the olfactory content can be an important factor for immersive user experience. The olfactory content is an additional element to enhance visual, audio contents by providing the emotional effects. But the olfactory content has not been used widely because olfactory systems should be connected with main contents system. Therefore the w...

We report a rare case of olfactory ensheathing cell tumor. A female presented a large soft mass extending medially to the olfactory cleft and laterally to the middle meatus in the left nasal cavity. Imaging studies confirmed a cystic mass extending superiorly into the frontal lobe, indicating that the tumor arouse from the olfactory mucosa. A subtotal resection was achieved through an endoscopi...

The olfactory bulbs have been examined in patients with Alzheimer's disease and compared with those in elderly undemented and younger undemented control patients. In Alzheimer's disease neurofibrillary tangles were found in the anterior olfactory nucleus but not elsewhere in the olfactory bulb. Cell loss in the anterior olfactory nucleus was also found in Alzheimer's disease. It is clear that t...

Axonal development and synapse formation in olfactory sensory neurons By Florencia Marcucci The olfactory epithelium (OE) possesses the rare capacity among neuronal tissues to regenerate throughout life. As a result, progenitor cells continuously proliferate and differentiate into olfactory sensory neurons (OSNs) that project their axons to the olfactory bulb (OB) where they establish connectio...

The capacity to form olfactory images has received less attention than the formation of visual and auditory images. The evidence in favor of such ability is also inconsistent. This thesis explored some of the characteristics of olfactory imagery through three empirical studies. Study I investigated the effects of blocking spontaneous sniffing during olfactory imagery. The results indicated that...

This study describes the functional anatomy of olfactory and visual naming and matching in humans, using positron emission tomography (PET). One baseline control task without olfactory or visual stimulation, one control task with simple olfactory and visual stimulation without cognition, one set of olfactory and visual naming tasks, and one set of olfactory and visual matching tasks were admini...

Characteristics The olfactory system is highly developed in vertebrates, particularly in “macrosmic” mammals (such as many rodents) where olfaction is the primary sensory system used to navigate in the world. As olfactory ability has evolved, there has been a concurrent increase in the size and complexity of cortical structures dedicated to encoding and deciphering olfactory information (▶corti...

Notch signalling plays an important role in synaptic plasticity, learning and memory functions in both Drosophila and rodents. In this paper, we report that this feature is not restricted to hippocampal networks but also involves the olfactory bulb (OB). Odour discrimination and olfactory learning in rodents are essential for survival. Notch1 expression is enriched in mitral cells of the mouse ...

SIR, in the recent paper by Gudziol et al. (2009), treatment of chronic rhinosinusitis lead to an increase of the olfactory bulb volume over a 3-month period, and they concluded that this was due to the restoration of olfactory function. In this letter, we point out another factor that may affect olfactory bulb volume: neuroinflammation regulated neurogenesis. The olfactory bulb volume is great...