نتایج جستجو برای: oligodendrogliomas

تعداد نتایج: 585  

2017
Patrick R. Maloney Vitor Nagai Yamaki Ravi Kumar Derek Johnson Christopher Hunt Mark E. Jentoft Michelle Clarke

This paper reviews a case of metastatic 1p/19q codeleted oligodendrioglioma causing diffuse osteosclerosis and pain. Primary central nervous system (CNS) tumors rarely metastasize outside the CNS, and metastatic oligodendroglioma is rarer still. The patient in this study had relief of pain after being treated with temozolomide. We discuss this rare presentation and potential treatment options, ...

Journal: :AJNR. American journal of neuroradiology 2008
G Brasil Caseiras J S Thornton T Yousry C Benton J Rees A D Waldman H R Jäger

We assessed the influence of inclusion (method 1) and exclusion (method 2) of intratumoral vessels when determining maximum relative cerebral blood volume (rCBVmax) in 3 types of low-grade gliomas (LGGs): astrocytomas, oligoastrocytomas, and oligodendrogliomas. Method 1 yielded significantly higher mean rCBVmax than method 2. However, only method 2 demonstrated a significant (P = .026) associat...

Journal: :Cancer research 2009
Hai Yan Darell D Bigner Victor Velculescu D Williams Parsons

Mutations of the isocitrate dehydrogenase (IDH) metabolic enzymes IDH1 and IDH2 have been found to be frequent and early genetic alterations in astrocytomas and oligodendrogliomas. All mutations identified to date affect a single amino acid located within the isocitrate binding site (R132 of IDH1 and the analogous R172 residue of IDH2). IDH1 and IDH2 mutations define a specific subtype of gliom...

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