Regional heterogeneities of ventricular repolarizing currents and their role in arrhythmogenesis have received much attention; however, relatively little is known regarding heterogeneities of intracellular calcium handling. Because repolarization properties and contractile function are heterogeneous from base to apex of the intact heart, we hypothesize that calcium handling is also heterogeneou...

INTRODUCTION The purpose of this study was to compare the accuracy of working length (WL) measurements by using the Root ZX II, Apex NRG XFR, and Mini Apex Locator with rotary nickel-titanium (NiTi) instruments. METHODS Twenty-eight teeth had their WLs determined with each electronic apex locator (EAL) by using 0.04 taper ProFiles sizes 40-20 in a crown-down technique until WL was reached. Fo...

The position of the apex beat in relation to the midclavicular and nipples lines and the intercostal spaces was studied in 353 healthy Jamaican children from birth to 10 years. The traditional use of the midclavicular line as a reference point in relation to the apex beat is not an accurate index of normal heart size at all ages. For this purpose actual measurement of the apex beat, which range...

We generalize the class of apex game by combining a winning coalition of symmetric minor players with a collection of apex sets which can form winning coalitions only together with a fixed quota of minor players. By applying power indices to these games and their subgames we generate players’ preferences over coalitions which we use to define a coalition formation game. We focus on strongly mon...

Characterization of the proteome of organelles and subcellular domains is essential for understanding cellular organization and identifying protein complexes as well as networks of protein interactions. We established a proteomic mapping platform in live Drosophila tissues using an engineered ascorbate peroxidase (APEX). Upon activation, the APEX enzyme catalyzes the biotinylation of neighborin...

Background Curved rocker shoes are designed with a contoured outsole which can be characteristics by three principle design features: rocker angle, apex angle and apex position. Although these shoes are routinely prescribed to reduce in-shoe pressure in patients with diabetes, there is only minimal scientific evidence to inform the choice of value for each of the three design features. Results ...

Pneumatization of the petrous apex was investigated in 226 subjects without middle ear disease by means of target imaging CT. The degree of pneumatization of all subjects was 32.7% (148/452 ears), but no difference in degree was revealed with distinction of bilateral ears or between sexes. In 148 ears with pneumatization of the petrous apex, a higher degree of pneumatization was found in larger...

Genetic sequences of multiple genes are becoming increasingly common for a wide range of organisms including viruses, bacteria and eukaryotes. While such data may sometimes be treated as a single locus, in practice, a number of biological and statistical phenomena can lead to phylogenetic incongruence. In such cases, different loci should, at least as a preliminary step, be examined and analyse...

Copyright @ 2015 Authors. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are properly cited. Julius July,1 Eka J. Wahjoepramon...

A comparative analysis is made which is grounded on literary data concerning the advantages and disadvantages of apex locators of various generations that have been created following two different principles /19, 28/. The PURPOSE of this study is to create a method and a device that combine the established advantages of fourth and fifth generation instruments. While measuring the working length...