Background Skin prick testing and serum food-specific IgE testing are the most commonly used diagnostic tests in evaluating IgE-mediated food reactions. However, the presence of negative tests can be falsely re-assuring such outcomes do not always exclude allergy. Food challenges are therefore indicated. Double-blind, placebo-controlled food challenge is the gold standard for diagnosis, but in ...

Background: The aim of the study was to investigate the prevalence of food allergy in patients referred to our Allergy Unit and to evaluate the diagnostic methods used. Methods: We selected 674 patients referred to the Allergy Unit of our hospital from May 2002 to October 2004. The prevalence of symptoms was determined by a standardized questionnaire, prick-prick test, and serum specific IgE. I...

BACKGROUND Food allergy is a disorder in which antigenic food proteins elicit immune responses. Animal models of food allergy have several limitations that influence their utility, including failure to recapitulate several key immunologic hallmarks. Consequently, little is known regarding the pathogenesis and mechanisms leading to food allergy. Staphylococcus aureus-derived enterotoxins, a comm...

cow’s milk allergy (cma) is the most frequent food allergy in children and oral immunotherapy (oit) is a promising approach for treatment of patients. the most challenging cases are anaphylactic with coexisting asthma and proposing safe protocols is crucial especially in high risk groups. considering that cma varies among patients, an individualized oit protocol would be beneficial to achieve a...

Methods We report the observations of two boys of age 5 and 11 formerly diagnosed with common food allergens. A secondary sensitization to pine nuts appears in skin prick tests using a commercial extract (Stallergènes, Antony, France). Specific serum IgE test (CAP-FEIA f253 Phadia) were performed. Because it was impossible to precise the consumption of pine nuts (anamnesis not informative enoug...

Results Case A 30-year-old Thai woman, who presented with a history of angioedema for 6 months. Her angioedema involved lip, eyelid and hand swelling. She was referred to our Allergy Clinic for further investigation. It was found that her symptoms of angioedema usually occurred in 30 minutes after ingesting navel orange and disappeared after 1-2 hours later. She favored in navel orange and she ...

In daily clinical practice, it is not so easy to make a confirma-tive diagnosis of food allergy. Interpretation of skin prick test and serum food-specific IgE (sIgE) test results is influenced by detailed clinical history of an individual patient, but ingested foods which provoke adverse reactions often contain many ingredients and lead to a misdiagnosis of food allergy. Oral food challenge is ...

Oral food challenge (OFC) tests are necessary in allergy practice.1-4 The spread of the Omicron variant severe acute respiratory syndrome coronavirus 2 significantly affected practice.5, 6 Universal pre-admission screening for disease 2019 (COVID-19) may effectively identify patients with asymptomatic COVID-19.7 However, no studies have reported influence COVID-19 pandemic and on number inpatie...