the aim of this study is to formulate a novel ophthalmic nanosuspension (ons), an alternative carrier system to traditional colloidal carriers for controlled release (cr) of acyclovir (acv). in the present study, ons is employed to avoid some of major disadvantages of colloidal carriers systems such as instability in cul de sac and short half life by increasing efficiency of drug encapsulation ...

DNA sequencing and microsatellite analyses were performed to investigate the relationship of Sri Lankan cutaneous leishmaniasis isolates to known species of Leishmania. This identified L. donovani as the agent of Sri Lankan cutaneous leishmaniasis, and showed these parasites are closely related to those causing visceral leishmaniasis in the Indian subcontinent.

purpose: to compare ophthalmic artery velocity in eyes with nonarteritic anterior ischemic optic neuropathy (naion) with that of normal fellow eyes. methods: in this case-control study, 20 patients with unilateral naion and disease onset less than 8 weeks, were enrolled. using color doppler imaging, mean, maximum systolic and end diastolic ophthalmic artery velocities were evaluated. the result...

introduction: the main purpose of this study was to evaluate the prevalence of ophthalmic injuries associated with mid-facial fractures in patients admitted to shahid beheshti university hospital in babol, iran, from 2002 to 2012. materials and methods: a cross-sectional, retrospective study was undertaken to determine the prevalence of ophthalmic injuries associated with mid-facial fractures i...

Leishmaniasis is a neglected tropical disease that requires timely and inexpensive treatment. For this purpose, nanoemulsion with polyene macrolide antibiotic, or amphotericin B (NE-AmB), was developed. This study quantified the amount of drug permeated retained in intact lacerated human skin, simulating cutaneous leishmaniasis (CL) processes. Toxicity macrophage keratinocyte cell lines, activi...

BACKGROUND There is paucity of data on quality of life as a dimension of treatment outcome among Visceral Leishmaniasis and HIV coinfected patients. This study sought to explore perceived quality of life among Visceral Leishmaniasis and HIV coinfected male migrant workers in Northwest Ethiopia. METHODS Twenty Visceral Leishmaniasis and HIV coinfected study participants took part in the in-dep...

Sandflies are small insects belonging to the order Diptera, which make up Phlebotominae subfamily within Psychodidae family. In fight against leishmaniasis in prefecture of Meknes, Morocco, a study phlebotomist population was carried out during period activity sandflies while studying link between abundance these and climatic factors, namely, temperature, moisture, rainfall, wind speed. A total...

Ophthalmic artery blood flow in 5 patients with internal carotid artery occlusion of sudden onset was monitored by an ultrasonic Doppler flowmeter to investigate the possible relationship to spontaneous recanalization of the occluded artery. The occluded internal carotid arteries of 2 patients were confirmed angiographically to recanalize and the reversed flow of their ophthalmic arteries chang...

BACKGROUND Kabuki syndrome is a multi-system disorder with peculiar facial features, and ophthalmic abnormalities are frequently involved. This case report of a child with Kabuki syndrome describes two new previously unreported ophthalmic conditions. CASE PRESENTATION A 3-year-old Taiwanese boy with Kabuki syndrome had a short stature, spinal dysraphism, intellectual disability and typical fa...