Dear Editor: Sterile ophthalmic injections with 2 antibiotics (ceftazidime and vancomycin) and 1 glucocorticoid (dexamethasone) are used at University Hospital of Geneva in some patients with infectious complications after intraocular surgeries. This is an off-label indication. They are administered as intravitre-ous injections and need to be prepared just before utilization , because the subst...

Timolol maleate has a molecular weight of 432.50. It is a white, odorless, crystalline powder which is soluble in water, methanol, and alcohol. Timolol maleate is stable at room temperature. Timolol maleate ophthalmic solution is supplied in two formulations: Ophthalmic Solution TIMOPTIC* (timolol maleate ophthalmic solution), which contains the preservative benzalkonium chloride; and Ophthalmi...

Abstract Background The goal of this study is to compare ophthalmic emergency room (OER) visits during the Coronavirus disease-19 (Covid-19) pandemic those a control period. Methods We compared all OER Meir Medical Center in Israel, from March 15th April 15th, 2020, Covid-19 and government mandated quarantine, same period 2019. Factors analyzed were patient demographics, chief complaints, refer...

PURPOSE To perform a comprehensive and systematic review regarding ophthalmic adverse drug reactions (ADRs) to systemic drugs to: (i) systematically summarize existing evidence, (ii) identify areas, ophthalmic ADRs or drugs that lacked systematization or assessment (namely drugs with original studies characterizing specific ophthalmic ADRs but without causality assessment nor without meta-analy...

Ophthalmia neonatorum is generally defined as conjunctivitis occurring within one month of life. The sources of this infection are environmental organisms or the organisms colonized in the birth canal. Untreated infection can cause blindness, especially if the corresponding organisms areNeisseria gonorrhoeae, or Chlamydia trachomatis. Povidone-iodine ophthalmic solution is an effective antib...

BACKGROUND Benzalkonium chloride (BAC) is a common preservative used in ophthalmic solutions. The aim of this study was to compare the cytotoxic effects of BAC-containing ophthalmic solutions with a BAC-free ophthalmic solution using an organotypic 3-dimensional (3-D) corneal epithelial model and to determine the effects of latanoprost ophthalmic solution and its BAC-containing vehicle on corne...

In 102 patients with angiographically proven occlusive carotid artery disease of 60-100% diameter reduction, Doppler ophthalmic artery pressure and blood flow direction were recorded by the recently developed ophthalmomanometry-Doppler technique. Among these 102 patients, 50 presented with complete carotid artery occlusions and 52 with carotid artery diameter stenoses of greater than or equal t...

Abstract Background: Thyroid eye disease (TED) is an unpredictable autoimmune inflammatory which can be sight-threatening, debilitating, and disfiguring. The majority of patients have mild, self-limited TED, 20-30% experience moderate/severe disease, 3-5% may develop sight-threatening such as CON or exposure keratopathy. Surgical intervention commonly necessary for with stable however, there li...