We present two cases of food and exercise-induced anaphylaxis (FEIA) in patients with a diagnosis of oral allergy syndrome (OAS) to the implicated foods. Patient A had FEIA attributed to fresh coriander and tomato and Patient B to fresh celery. These food allergens have been implicated in OAS and have structural antigenic similarity to that of birch and/or grass. Both patients' allergies were c...

BACKGROUND Burning mouth syndrome (BMS) is a burning or sore mouth in the absence of changes in the oral mucosa. It is often difficult to diagnose and treat. Numerous theories of the etiology have been suggested, including contact allergy. OBJECTIVE To determine the clinical utility of patch testing in patients with BMS. METHODS We retrospectively reviewed the charts of patients diagnosed w...

PURPOSE OF REVIEW Advances in the prevention and treatment of food allergy have been published in the last few years and are placed in context using a review format. RECENT FINDINGS Preventing food allergy has been studied for years with questions of whether avoidance or exposure was a better strategy. Recent research has suggested that peanut allergy can be substantially reduced in high-risk...

Two cases of patients with food and exercise-induced anaphylaxis (FEIA) with confirmed allergies to oral allergy syndrome are herein presented. Patient A had food anaphylaxis to fresh coriander and tomato and Patient B to fresh celery. These food allergens have structural antigenic similarity to that of birch and/or grass. Both patients’ allergies were confirmed by fresh prick-to-prick tests. I...

BACKGROUND Food allergy is a disorder in which antigenic food proteins elicit immune responses. Animal models of food allergy have several limitations that influence their utility, including failure to recapitulate several key immunologic hallmarks. Consequently, little is known regarding the pathogenesis and mechanisms leading to food allergy. Staphylococcus aureus-derived enterotoxins, a comm...

According to the position paper from the European Academy for Allergy and Clinical Immunology (EAACI) “food allergy” summarizes immune-mediated, non-toxic adverse reactions to foods (Figure 1)(Bruijnzeel-Koomen et al., 1995). The most common form of food allergy is mediated by immunoglobulin (Ig)E antibodies and reflects an immediatetype ("Type 1 hypersensitivity") reaction, i.e. acute onset of...

BACKGROUND Cow's milk allergy is the most prevalent food hypersensitivity, affecting 2-3% of infants, but it tends to resolve with age. Cow's milk-specific immunoglobulin E in the serum is an important measure in the diagnosis and follow-up of infants and children with cow's milk allergy. OBJECTIVES To examine the relation between CmsIgE and the probability of resolution of milk allergy. ME...

Crustacean shellfish allergy is an important cause of food allergy and anaphylaxis in Asia. The major allergen in shellfish allergy is tropomyosin, a pan-allergen that is also found in house dust mites and cockroaches. Tropomyosins from house dust mites (HDMs) have a high sequence homology to shellfish tropomyosins, and cross-reactivity between HDM and shrimp tropomyosins has been demonstrated....

BACKGROUND To examine if patients with oral lichen planus, oral lichenoid lesions and generalised stomatitis and concomitant contact allergy have more frequent and severe xerostomia, lower unstimulated and chewing-stimulated saliva and citric-acid-stimulated parotid saliva flow rates, and higher salivary concentration of total protein and sIgA than cases without contact allergy and healthy cont...