The oral cavity is the primary site of verbal human communication. It has many additional important functional roles, including bolus preparation and formation, taste, and deglutition. Oral cavity cancer treatment, particularly for advanced tumors (because of radical surgery), destroys the integrity of this area. Extensive reconstructive efforts are required to maintain oral continuity, to faci...

BACKGROUND The incidence of oral cavity cancer (OCC) is not well documented because it is rarely described in accord with the anatomic definition but is usually grouped with oropharyngeal subsites. We studied the incidence of OCC in developed and in developing countries. METHODS The age-standardized and age-specific incidence rates of OCC were calculated for the period 1998-2002, using the to...

OBJECTIVE The immune compromised patients after treatment of oral cancer may have a chance of infection by drug-resistant opportunistic microbes. We investigated the occurrence of opportunistic microorganisms in aged individuals receiving follow-up examinations after treatment of oral cancer in China. MATERIAL AND METHODS These patients were used as test group and the respective age grouped h...

The word chemoprevention includes prevention of initiation, promotion, and progression of carcinogenesis to cancer. This article is an attempt to review the dietary chemopreventive agents and their mode of action in chemoprevention of oral premalignant lesions and oral cancer using a systematic approach. Selected chemoprevention trials are discussed with a focus on strategies of trial design an...